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Coronary veins determine the pattern of sympathetic innervation in the developing heart

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Figure

Fig. 1. Cardiac nerves align with large diametercoronary vessels in the dorsal ventricular wall of
Fig. 2. Cardiac sympathetic axons associate with largediameter coronary veins within the subepicardiallayer of the dorsal ventricular wall.A-HtaulacZ/+
Fig. 3. Defective coronary development leads toabnormal sympathetic innervation. (A-D) Dorsalventricular walls of Gata5-Cre; β-cateninflox/flox mutants (B,D)
Fig. 4. VSMCs cover nerve-associated large diameter coronary veins.(A-D�) Visualization of coronary VSMCs in the subepicardium
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