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Methanol extract of semen Ziziphi Spinosae attenuates ethanol withdrawal anxiety by improving neuropeptide signaling in the central amygdala

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Academic year: 2020

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Figure

Fig. 1 (a) HPLC profile of MESZS, which includes magnoflorine, spinosin, and 6′′′-feruloyl spinosin
Fig. 2 Effects of MESZS on the behavioral changes of rats in the open field test. All data are expressed as a mean ± SEM (n = 8)
Fig. 3 Effects of MESZS on the behavioral changes of rats in the elevated plus maze test
Fig. 4 Effects of MESZS on plasma CORT concentrations during EtOHW. Withdrawal from chronic EtOH administration increased plasma CORTlevels in rats, which was prevented by MESZS treatment
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