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Modulation of major histocompatibility complex (MHC) class i heavy chain gene expression by naringenin in cells that express human papillomavirus (HPV) E6 and E7 genes

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Academic year: 2020

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Figure

Figure 1.culture and aliquots (10 µβg) of RNA analysed by Northern blotting and hybridization with either a nick-translated H-2Ka) or -actin insert (panel b)
Figure 2.   The effect of different concentrations of Naringeninextracts of cells treated with Naringenin or 100% ethanol by thaton MHC class I heavy chain promoter activity in 3Y1 cells
Figure 4.   The effect of Naringenin on MHC class I promoteractivity in 3Y1 cells expressing HPV E6 or E7 gene products.The H2K-CAT plasmid was co-transfected with either the controlplasmid (pUC19) or HPV 6 E6, HPV 6 E7, HPV 16 E6, HPV 16 E7 plasmids and was treated for 24hrs with 300µg/mlnaringenin

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