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The Shh receptor Boc is important for myelin formation and repair

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Figure

Fig. 1. Boc is expressed in neurons and neural progenitors of the dorsal forebrain germinative zone
Fig. 2. Boc regulates the perinatal production of neural progenitors and OPCs. (A) Immunostaining of slices derived from P0-P1 wild-type or*animal or one culture
Fig. 3. Boc KO mice display a decreased production of myelin in the developing dorsal forebrain
Fig. 4. The Bocupregulation in APC mutant fails to induce actin disassembly proteins and leads to a delay of myelination
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