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Identification of DNA-PKcs as a primary resistance factor of salinomycin in osteosarcoma cells

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Academic year: 2020

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Figure

Figure 1: DNA-PK inhibitors dramatically potentiate salinomycin-induced cytotoxicity in OS cells
Figure 2: Salinomycin’s sensitivity in OS cells is increased with DNA-PKcs knockdown, but decreased with DNA-PKcs over-expression.figure were repeated three times, and similar results were obtained
Figure 3: miR-101 downregulates DNA-PKcs and augments salinomycin’s cytotoxicity in OS cells
Figure 4: DNA-PKcs is required for salinomycin-induced autophagy activation in OS cells
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