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Beyond comparisons of means: understanding changes in gene expression at the single cell level

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Figure

Fig. 1 Graphical representation of our model for detecting changes in expression patterns (mean and over-dispersion) based on comparing twonumber of mRNA molecules for a technical geneμeach populationpredefined population of cells
Fig. 2 Estimated LFCs in expression (mean and over-dispersion) when comparing SCs vs P&S samples (2i serum culture)
Fig. 3b). In fact, counter-intuitively, 4710 genes (≈50 %of all analyzed genes) are highlighted to have a changein overall expression when using = 0
Fig. 4 Posterior estimates of model parameters based on random permutations of the mESC cell-cycle data set
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