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ddClone: joint statistical inference of clonal populations from single cell and bulk tumour sequencing data

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Figure

Fig. 2 Simulated phylogenetic tree (panelby setting entries with non-zero variant allele copy number to one ((genotypes a) and the resulting binarized cell genotype matrix (panel b)
Fig. 3 Performance analysis in presence of sampling distortion. Effect of sampling distortion on V-measure index (panelof cellular prevalences (panel a) and mean absolute error b) across multiple values for the total number of single cells (specified on to
Fig. 4 Benchmarking results over simulated data. Performance results for ddClone, single cell-only, and bulk data methods on ten synthetic50 cells sampled from a Dirichlet-multinomial distribution withdatasets
Fig. 5 Performance analysis in presence of doublets. Effect of presence of doublets on V-measure index (panelsimulated datasets each with 10 genotypes and 48 genomic loci
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