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Input source and strength influences overall firing phase of model hippocampal CA1 pyramidal cells during theta: Relevance to REM sleep reactivation and memory consolidation

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Academic year: 2020

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FIGURE 1.A: Schematic of realistic CA1 pyramidal neuronpartment at 328model. B: Theta drive conductances injected to proximal compart-ment at 100 lm from soma center (solid trace) and to distal com- lm from soma center (dashed trace)
FIGURE 2.Phases of spikes fired in response to a proximal1.5 nS) and distal dendritic stimulus (B) (injected 418soma center,dendritic stimulus (A) (injected 50 lm from soma center, gstim 5 lm from gstim 5 1.5 nS) over 50 runs of the model with back-
FIGURE 3.Phases of spikes fired in response to stimuli of(A–C) (at 50tion (D–F) (at 418varying amplitude gstim injected at a proximal dendritic location lm from soma center) and at a distal dendritic loca- lm from soma center) when background syn-aptic noise was present in the model (asterisks) and when it was
FIGURE 4.Voltage traces at the soma and at various dendriticlus (B) (injected at 418locations in response to a proximal stimulus (A) (injected at 50 lmfrom soma center, gstim 5 1.6 nS, as in Fig
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