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Review Article Somatic mutations of the EGF receptor and their signal transducers affect the efficacy of EGF receptor-specific tyrosine kinase inhibitors

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Academic year: 2020

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Figure

Figure 1. Model structure of the unliganded and liganded epidermal growth factor receptor (EGFR)
Figure 2. Schema of simplified signal transduction pathways through EGFR, and molecular mechanisms associated with sensitivity to EGFR-tyrosine kinase inhibitor (TKI)

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