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Cellular prion protein controls stem cell-like properties of human glioblastoma tumor-initiating cells

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Academic year: 2020

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Figure

Figure 1: A. Representative immunoblot analysis of PrPof PrPMTT reduction test. Values, taken as percentage of the values at time 0, are the average of two independent experiments, performed in quadruplicate
Figure 2: A. Prion protein mRNA expression in GBM1 (left) and GBM2 (right), evaluated by quantitative RT-PCR
Figure 3: A-B. Proliferation curves of GBM1-PrP-KO and GBM1-Scr (A) and GBM2-PrP-KO and GBM2-Scr (B) cells assessed by MTT assay after 24, 48 and 72 hours
Figure 4: A. Quantification of clonogenic activity of GBM1- and GBM2- Scr and PrP-KO cells, expressed as percentage of the number of plated cells, assumed as 100%
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