Tumor suppressor role of microRNA-1296 in triple-negative breast cancer

To determine if miR-34a promoted tumor-suppressive phenotypes in TNBC, we transfected a panel of breast cancer cell lines with 30nM miR-34a or scrambled control (miR-Scr), and

Even some people who have had breast cancer do not understand the differences between triple- negative breast cancers and breast cancers that are hormone receptor-positive

Among the different subtypes, triple negative breast cancer (TNBC) is characterized by the total absence of the estrogen-receptor (ER) and progesteron-receptor (PR) expression as

Figure 2 Effects of inducible nitric oxide synthase (iNOS) inhibitors on tumor cell proliferation, migration, and mammosphere formation in triple-negative breast cancer (TNBC)

Our results specifically implicate tumor cell-produced MMP9 in invasion and metastatic progression in models of basal-like triple negative breast cancer, and suggest MMP9 as a

We tested a number of multi-target kinase inhibitors (imatinib, sunitinib, pazopanib and dasatinib) in Her-2 positive and triple negative breast cancer cell lines, alone

(A, C) and Matrigel invasion (B, D) assays on MDA-MB-231 and MDA-MB-468 cells transfected with miR-455-3p mimics, miR-455-3p inhibitor or negative control showed miR-455-3p

Inhibition of acetyl-STAT3 by SH-I-14 resulted in disruption of STAT3-DNMT1 interaction, de-methylation of TS genes’ promoter regions in triple-negative breast cancer (TNBC)