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A novel DFP tripeptide motif interacts with the coagulation factor XI apple 2 domain

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Figure

Figure 1. FXI binding peptides with the DFP motif.(A) Alignment of peptide sequences from the randomscreen, with 37 peptides shown containing the DFPtripeptide
Table 1. Crystallographic data collection and refinement statistics
Figure 2. FXI peptide complex structures. (A)Cartoon diagram showing only the apple 2 domain inwhite, with laminin LP2 peptide shown as sticks inpurple
Figure 3. HK amino acid sequences and interaction with FXI. (A) The HK C-terminal domain 6 amino acid sequence alignment derived from the National Center forBiotechnology Information HOMOLOGENE server for different species is indicated
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