Monthly Weather Bulletin May 2012

To that end, we found that pharmacological inhibition of Usp9X sensitized patient-derived xenograft cells (GBM12) to the cytotoxic effects of ABT263 and that this effect is

A much higher level of GPR160 expression was observed in human prostate cancer cells such as PC-3, DU145, LNCaP and 22Rv1 (Figure 1B).. PC-3 and DU145 cells are

Specifically, we determined whether CFTR is expressed in the proximal colon and how its expression in the colonic epithelium compares with that of NKCC1 and pNBCe1, the main

By western blot analysis the low dose of MLN-8237 induced cleaved PARP and caspase 3 along with induction of phospho H3 (S0), p53, p21 and Aurora A consistent with an Aurora A

S slow-down reached significance in the double treated group receiving one [ 131 I]ICF01012 injection (25 MBq) and 1 mg of coDbait, this effect might be emphasized when treatment

Treatment of HuH7 hepatoma or HT1080 sarcoma cells with OSU-03012 +/− sildenafil or sorafenib +/− sildenafil resulted in a rapid dose- and time-dependent reduction

There are a number of different approaches to DEB model formulation, but the ‘standard’ DEB model (Kooijman, 2010; Sousa et al., 2010) is the only model known to the authors

The tumor growth was similar between the 2 models derived from the same patient, respectively from the metastatic lymph node and the primary tumor (Mel-X4 and Mel-X6) (mean