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14-Feb-08 D. Protti - University of Victoria and City University London

1

Electronic Prescribing (eRX)

Good News (and Sad News) Stories From

Around the World

II Andalusia Rational Drug Utilization Conference

Sevilla, Andalucia

October 26, 2007

(2)

14-Feb-08 D. Protti - University of Victoria and City University London

2

(3)

14

14--FebFeb--0808 D. Protti D. Protti --University of Victoria and City University LondonUniversity of Victoria and City University London 33

Outline

Outline

1.

1.

Setting the scene

Setting the scene

2.

2.

Good news stories (in primary care) from

Good news stories (in primary care) from

recent international studies

recent international studies

3.

3.

Sad news stories from North America

Sad news stories from North America

4.

4.

How does Andalucia compare?

How does Andalucia compare?

5.

(4)

14

14--FebFeb--0808 D. Protti D. Protti --University of Victoria and City University LondonUniversity of Victoria and City University London 44

Outline

Outline

1.

1.

Setting the scene

Setting the scene

2.

2.

Good news stories (in primary care) from

Good news stories (in primary care) from

recent international studies

recent international studies

3.

3.

Sad news stories from North America

Sad news stories from North America

4.

4.

How does Andalucia compare?

How does Andalucia compare?

5.

(5)

14-Feb-08 D. Protti - University of Victoria and City University London

5

IOM Reports on

1. Preventing Medication Errors

(6)

14-Feb-08 D. Protti - University of Victoria and City University London

6

IOM Report Findings



44,000 – 98,000 unnecessary deaths in the US.



Even using the lower estimate, more people die

from clinical mistakes each year than from

highway accidents, breast cancer, or AIDS



7,000 Americans are die each year from

medication errors alone

– approximately 16%

more than the number attributable to work-related

injuries



Medical errors cost the U.S. approximately $38

billion per year, with about $17 billion of those

costs associated with preventable errors

(7)

14-Feb-08 D. Protti - University of Victoria and City University London

7

At least 1.5 million preventable ADEs occur

each year in the United States

Hospitals: ~400,000

Ambulatory Care: ~530,000

Long-term care: ~800,000

Likely underestimates!

In 2004, the US Pharmacopeia MEDMARX system identified the

sources of medication reconciliation errors.

66% occurred

during the patient's transition or transfer to another level of care

,

22% during the patient's admission to the facility, and 12% at the

time of discharge.

(8)

How Hazardous Is Health Care?

Number of encounters for each fatality

Total lives lost per year

1

10

100

1,000

10,000

100,000

1,000,000

10,000,000

DANGEROUS

DANGEROUS

REGULATED

REGULATED

ULTRA

ULTRA

-

-

SAFE

SAFE

(>1/1000)

(<1/100K)

1

100,000

10,000

1,000

10

100

Health

Care

Mountain

Climbing

Bungee

Jumping

Driving

Chemical

Manufacturing

Chartered

Flights

Scheduled

Airlines

European

Railroads

Nuclear

Power

(9)

14-Feb-08 D. Protti - University of Victoria and City University London

9

Risk of Death as an Airline Passenger and as a Patient

Admitted to an Acute Care in Hospital in Canada

0.0 deaths in 9.5million

flights

2

South West Airlines

7,400 – 19,000 deaths in 2

million patient admissions

3

Canadian acute care hospitals

0.67 deaths in 2 million

passengers

2

Air Canada

1 death in 2 million

passengers

1

Airline industry

1.

Leape LL et al Reducing Adverse Drug Events, IHI, 1998.

2.

According to AirSafe.com

3.

By extrapolation from Baker GR, Norton PG et al The Canadian Adverse Events Study,

JMAC 25 May 2004; 1684.

(10)

14-Feb-08 D. Protti - University of Victoria and City University London

10

Patient safety

ƒ

Between 1.5%-4.0% prescriptions

are in error with serious patient

risk

ƒ

Adverse drug events occur in

5%-18% of ambulatory patients

Quality of care - Compliance

ƒ

20% of scripts are never filled

ƒ

Patient satisfaction is declining

Cost of errors: $2 billion / year

Impact on productivity*

ƒ

Physician practice: 3 hours per

day

ƒ

Pharmacy: 4 hours per day (up to

1 call per Rx)

ƒ

Inefficient delivery

z

Illegible

handwriting

z

Phone tag and

fax tag

z

Patient waiting

in the

pharmacy

Rx

Rx

Rx

(11)

14-Feb-08 D. Protti - University of Victoria and City University London

11

American physicians write

4.5 billion prescriptions

each year. . . .

On Paper

!

The Challenge of “Prescription Hand-offs”

Illegible Handwriting

Unclear Abbreviations and Doses

Verbal Communication Among

(12)

1.

Ability to create a prescription electronically

2.

Ability to receive automated decision support during script creation



Drug interactions, drug-allergy, etc.



Medication lists and information



Eligibility determination



Formulary coverage from insurer including co-pay information



Prior authorization

3.

Ability to send script electronically to a pharmacy using standard transmission

messaging



Electronic Prescribing is not faxing or printing paper prescriptions

4.

Ability for a pharmacy to process electronic script in their system

5.

Ability to receive/authorize pharmacy initiated-renewals electronically

6.

Ability to determine “fill status” as a measure of compliance (medication history)

7.

Potential for information sharing with other health care partners



Medication History



Eligibility/formulary information



Patients

(13)

14-Feb-08 D. Protti - University of Victoria and City University London

13

(14)
(15)
(16)
(17)



823 million visits to

physician offices in 2000

1



4 out of 5 patients who visit

a physician leave with at

least one prescription

2



65% of the US population

(91% of Medicare) use a

prescription medication each

year

3

1) Pastor PN et. al. Chartbook on trends in the health of Americans. Health, United States, 2002. National Center for Health Statistics. 2002. 2) The chain pharmacy industry profile. National Association of Chain Drug Stores. 2001.

3) Agency for Healthcare Research and Quality. MEPS Highlights #11: distribution of health care expenses, 1999.

3.5 Billion Total Filled Prescription

Transactions in 2003

1.4 B 0.4 B 0.5 B 1.5 B

Refills

New Scripts

Renewals

Unfilled

(18)

14-Feb-08 D. Protti - University of Victoria and City University London

18

Limitations of this talk



In the interests of time



Focus will be almost exclusively on primary care

versus secondary (acute hospital inpatient) care



Little on CPOE, decision support, bar medication

administration, medication administration records



e-Rx is more common in 1

0

care than 2

0

care



Documented benefits are coming from both

(19)

14

14--FebFeb--0808 D. Protti D. Protti --University of Victoria and City University LondonUniversity of Victoria and City University London 1919

Outline

Outline

1.

1.

Setting the scene

Setting the scene

2.

2.

Good news stories (in primary care) from

Good news stories (in primary care) from

recent international studies

recent international studies

3.

3.

Sad news stories from North America

Sad news stories from North America

4.

4.

How does Andalucia compare?

How does Andalucia compare?

5.

(20)

14-Feb-08

D. Protti - University of Victoria and City University London

20

A Comparison of Information

Technology in General Practice in

Ten Countries

International Study Conducted by

Denis Protti

(21)

14-Feb-08

D. Protti - University of Victoria and City University London

21

Background to the study

• Commissioned by Canada Health Infoway

– Goal: to identify the governmental, collegial,

technological, and other factors contributing to the

high levels of office automation in GP practices

– In all 10 countries,

primary care physicians

had

computers (EMR) in their office that were used

for

clinical purposes

(22)

14-Feb-08

D. Protti - University of Victoria and City University London

22

Data collected in 2005 - 06

• Australia

• Austria

• Denmark

• England

• Germany

• Netherlands

• New Zealand

• Norway

• Scotland

• Sweden

(23)

14-Feb-08

D. Protti - University of Victoria and City University London

23

Data was collected from

• Personal interviews with GPs, ministerial and

vendor representatives

• Scientific literature

• OECD, government, and professional

association reports and web sites

Data quality ranges from very robust and

trustworthy to ‘estimates’ based on small

sample sizes

(24)

14-Feb-08

D. Protti - University of Victoria and City University London

24

% GPs with electronic prescribing of medications

(with varying degrees of decision support re: alerts, etc.)

• Australia

Most

• Austria

Most

• Denmark

Most

• England

Most

• New Zealand

Most

Most = >75%

Many = >50%

• Norway

Most

• Scotland

Most

• Sweden

Most

• Germany

Many

• Netherlands

Many

Some = >25%

Few = <25%

(25)

Primary Care Doctors Use of Electronic Patient

Medical Records, 2006

79

23

42

98

92

89

28

0

25

50

75

100

AUS

CAN

GER

NET

NZ

UK

US

Percent

(26)

Practice Use of Electronic Technology

(from Schoen et al Commonwealth Fund study)

48

84

90

78

34

27

76

Electronic access to

patients’ test results

40

19

44

11

7

15

12

Electronic access to

patients’ hospital

records

55

20

UK

59

27

GER

78

62

NZ

20

85

11

81

Electronic prescribing

of medication

22

5

8

65

Electronic ordering of

tests

US

NET

CAN

AUS

Percent reporting

routine use of:

(27)

14-Feb-08

D. Protti - University of Victoria and City University London

27

% GPs transmitting medication prescriptions

• Denmark

Most

• Sweden

Many

• England

Some

• Australia

Few

• Austria

Few

Most = >75%

Many = >50%

• Germany

Few

• Netherlands

Few

• Scotland

Few

• New Zealand

None

• Norway

None

Some = >25%

(28)

14-Feb-08

D. Protti - University of Victoria and City University London

28

Benefits of automation in GP practices

(ranked scale of 1-8)

Simplified Repeat Prescription

– #1 in Scotland and Sweden

– #2 in all other countries, except Norway (#3) and NZ (#4)

Saving time

– #1 in Australia, England, Germany, Netherlands and New

Zealand

(29)

Prescribers

Office staff

Minutes

per day

(30)

14-Feb-08

D. Protti - University of Victoria and City University London

30

Benefits of automation in GP practices

(ranked scale of 1-8)

• Quicker receipt of results –

range:1-5

• Easier to find records –

range:1-5

• Legibility of records and form –

range: 3-7

• More timely communication with other clinicians –

range: 1-8

• Availability of clinical data on Intranet or Internet –

range: 3-8

(31)

14-Feb-08

D. Protti - University of Victoria and City University London

31

A

crude

ranking of the 10 countries

Most = 4

,

Many = 3

,

Some = 2

,

Few = 1

Based on only 5 variables

% GPs:

1. with electronic prescribing of medications

2. recording progress notes

3. transmitting medication prescriptions

4. receiving laboratory results

5. receiving discharge summaries

(32)

14-Feb-08

D. Protti - University of Victoria and City University London

32

A

crude

ranking of the 10 countries

(Most = 4, Many = 3, Some = 2, Few = 1)

Denmark (20)

Scotland (15)

New Zealand (14)

Sweden (14)

England (13)

The Netherlands (12)

Australia (11)

Austria (10)

Norway (10)

Germany (7)

(33)

Primary Care Practices with Advanced

Information Capacity

*Count of 14: EMR, EMR access other doctors, outside office, patient; routine use electronic ordering

tests, prescriptions, access test results, access hospital records; computer for reminders, Rx alerts, prompt

tests results; easy to list diagnosis, medications, patients due for care.

Percent reporting 7 or more out of 14 functions

*

Source: 2006 Commonwealth Fund International Health Policy Survey of Primary Care Physicians

87

83

72

59

32

19

8

0

25

50

75

100

(34)

14-Feb-08

D. Protti - University of Victoria and City University London

34

Comparing the Commonwealth Fund and

the Protti Rankings

CF rankings

(7 functions)

1. New Zealand (87)

2. United Kingdom (83)

3. Australia (72)

4. Netherlands (59)

5. Germany (32)

Protti rankings

(5 functions)

1. New Zealand (14)

2. England (13)

3. Netherlands (12)

4. Australia (11)

5. Germany (7)

(35)

14

14--FebFeb--0808 D. Protti D. Protti --University of Victoria and City University LondonUniversity of Victoria and City University London 3535

Outline

Outline

1.

1.

Setting the scene

Setting the scene

2.

2.

Good news stories (in primary care) from

Good news stories (in primary care) from

recent international studies

recent international studies

3.

3.

Sad news stories from North America

Sad news stories from North America

4.

4.

How does Andalucia compare?

How does Andalucia compare?

5.

(36)

14-Feb-08 D. Protti - University of Victoria and City University London

36

Canada - medication safety has become an

area of increasing awareness



However,

72% of primary care doctors in

Canada reported that it was somewhat or very

difficult to generate lists of all of the medications

taken by individual patients

,

if at all, including

those prescribed by other doctors.

International Health Policy Survey of Primary Care Doctors

Commonwealth Fund: 2006

(37)

14-Feb-08 D. Protti - University of Victoria and City University London

37

Canadian situation



Approximately 9,250 – 23,750 patients die annually due

to preventable adverse events (harm experienced by

patients given a drug but not necessarily caused by the

drug)



Adverse drug events (ADEs) refer to episodes of harm

caused by a drug.

Many such events are related to

medication errors or inappropriate drug use.

Baker, G.R., P.G. Norton, et al.

The Canadian Adverse Events Study: the incidence of adverse events among hospital

patients in Canada

Canadian Medical Association Journal. 170:1678-86. 2004

(38)

14-Feb-08 D. Protti - University of Victoria and City University London

38

Canadian situation

(cont’d)



Only 11% of primary care doctors in Canada use

electronic prescribing

- the lowest of all of the

surveyed countries.



This compares to over 80% in both the Netherlands

and Australia, which both reported a high

percentage of doctors using electronic prescribing

(85% and 81%, respectively).

(39)

United States situation



3.2 Billion Prescriptions Written Annually…



Only 20% of prescriptions are electronically

prescribed with 80% still handwritten



Most electronic prescriptions are still sent by

FAX

Sources: eHealth Initiative, 2004 and: Center for Information Technology Leadership, “The Value of

Computerized Provider Order Entry in Ambulatory Settings,” 2003.

National savings from universal adoption of

electronic prescribing systems

(40)

14-Feb-08 D. Protti - University of Victoria and City University London

40



33% of health care IT

professionals said that

CPOE

has had the greatest impact on

boosting patient care



50% respondents said that the

biggest challenge that IT

presents to patient care is that

health care providers are

unwilling to enter data

electronically

Healthcare Information and Management

Systems Society, October 11, 2007

(41)

Pen

Print

ª

6%

Fax

ª

37%

EDI

+

Decision

Support

ª

61%

(42)

American exception – The Veterans Administration

(Total…Daily Statistics)

Documents

(Progress Notes, Discharge Summaries, Reports)

779,000,000

…….. +

577,000

each workday

Orders

1.54 Billion………... +906,000 each workday

Images

425,000,000

……… +60

8,000

each workday

Vital Sign Measurements

957,000,000

……… +

665,000

each workday

Medications Administered with the Bar Code system

754,000,000……..…… +597,000 each workday

(43)

-20% -10% 0% 10% 20% 30% 40% 50%

VHA Cost Per Patient Avg. Medicare Payment/Enrollee Medical CPI

VHA Cost Per Patient - -0.3% 0.8% -6.2% -8.6% -6.5% -7.3% -9.1% -4.6% 0.8% Avg. Medicare Payment/Enrollee 6.4% 14.9% 14.9% 12.8% 14.9% 25.5% 31.9% 40.4% 44.7% Medical CPI - 3.3% 5.9% 9.8% 13.5% 18.4% 23.7% 29.5% 34.7% 39.4% 1995 1996 1997 1998 1999 2000 2001 2002 2003 2004

10 Year Cumulative

% Change in Costs - VA, Medicare, CPI

VHA Cost per Patient–

Total Medical Care Obligations per Total Unique Patients (inc non Veterans) • Average Medicare Payment per (www.cms.hhs.gov/resea rchers/pubs/datacompen dium) • Medical Consumer Price Index-- Bureau of Labor Statistics

(44)

14

14--FebFeb--0808 D. Protti D. Protti --University of Victoria and City University LondonUniversity of Victoria and City University London 4444

Outline

Outline

1.

1.

Setting the scene

Setting the scene

2.

2.

Good news stories (in primary care) from

Good news stories (in primary care) from

recent international studies

recent international studies

3.

3.

Sad news stories from North America

Sad news stories from North America

4.

4.

How does Andalucia compare?

How does Andalucia compare?

5.

(45)

14-Feb-08

D. Protti - University of Victoria and City University London

45

% GPs with electronic prescribing of medications

(with varying degrees of decision support re: alerts, etc.)

Andalucia

Most

• Australia

Most

• Denmark

Most

• England

Most

• New Zealand

Most

• Norway

Most

Most = >75%

Many = >50%

• Scotland

Most

• Sweden

Most

• Austria

Many

• Germany

Many

• Netherlands

Many

Canada

Few

United States

Few

Some = >25%

(46)

14-Feb-08

D. Protti - University of Victoria and City University London

46

% GPs transmitting medication prescriptions

Andalucia

Most

• Denmark

Most

• Sweden

Many

• England

Some

• Australia

Few

• Austria

Few

Most = >75%

Many = >50%

• Germany

Few

• Netherlands

Few

• Scotland

Few

United States

Few

• New Zealand

None

• Norway

None

Canada

None

Some = >25%

(47)

14-Feb-08

D. Protti - University of Victoria and City University London

47

A

crude

ranking of 13 “jurisdictions”

in terms of e-prescribing

(Most = 4, Many = 3, Some = 2, Few = 1)

Andalucia (8)

Denmark (8)

Sweden (7)

England (6)

Australia (5)

Scotland (5)

Austria (4)

Germany (4)

New Zealand (4)

Norway (4)

The Netherlands (4)

»

United States (2)

»

Canada (1)

(48)

14

14--FebFeb--0808 D. Protti D. Protti --University of Victoria and City University LondonUniversity of Victoria and City University London 4848

Outline

Outline

1.

1.

Setting the scene

Setting the scene

2.

2.

Good news stories (in primary care) from

Good news stories (in primary care) from

recent international studies

recent international studies

3.

3.

Sad news stories from North America

Sad news stories from North America

4.

4.

How does Andalucia compare?

How does Andalucia compare?

5.

(49)

14-Feb-08 D. Protti - University of Victoria and City University London

49

The evidence that IT can enhance patient

safety and reduce costs is mounting



Boston’s Brigham and Women’s Hospital, demonstrated

that CPOE

reduced error rates by 55%

-- from 10.7 to 4.9

per 1000 patient days.



LDS Hospital in Salt Lake City demonstrated

a 70%

reduction in ADEs

after implementation of a CPOE system.



A study published in the Journal of Managed Care

Pharmacy in May 2005 reported

the average cost per

prescription was reduced by $2.57

and the per member per

month drug cost was reduced by $1.07 in those physician

practices equipped with full e-prescribing

.

(50)

14-Feb-08 D. Protti - University of Victoria and City University London

50

The IT Value Iceberg



Computers are just

the catalyst



Value comes from:



People who know

what to do with the

information



People who can

effect change

and innovation

(51)

Change management. Lessons learned

ƒ

Balance between deployment of those modules that ease involvement

and those that the Organization demands. Usability and adaptability vs.

Regulation from the upper levels of the organization (political level).

ƒ

Involve professionals in the inception of the system in order to create

useful tools for the clinical practice.

ƒ

Feedback of the information introduced in the system.

ƒ

Provide support to the management level information systems.

ƒ

Staff involvement.

ƒ

Political support.

ƒ

Explain crisis.

ƒ

Peer to peer training.

ƒ

Support to professionals:

ƒ

Field

ƒ

Contact centre

(52)
(53)

14-Feb-08 D. Protti - University of Victoria and City University London

53



“Against a background of an explosively growing

body of knowledge in the health sciences, current

models of clinical decision making by autonomous

practitioners, relying upon their memory and

personal experience, will be inadequate for

effective twenty-first-century health care delivery.”

Masys D

Effects Of Current And Future Information Technologies On The Health Care Workforce

HEALTH A F FA I R S, P. 33, Vo l. 2 1, No. 5, 2002

(54)

14-Feb-08 D. Protti - University of Victoria and City University London

54

1. Patient Safety

“The decision support feature of the in-patient

EMR identified 164,250 drug-drug, drug-allergy,

drug-food, and drug-duplication alerts, resulting

in 82,125 beneficial changes in treatment.”

Heib B, Handler T, Purchase E.

How to Gain Value From Physician Order Entry.

Strategic Analysis Report. Gartner; September 23, 2002.

Benefits

(55)

14

14--FebFeb--0808 D. Protti D. Protti --University of Victoria and City University LondonUniversity of Victoria and City University London 5555

Finite

Finite

Gracias

Gracias

[email protected]

[email protected]

(56)

14

14--FebFeb--0808 D. Protti D. Protti --University of Victoria and City University LondonUniversity of Victoria and City University London 5656

Additional Materials

(57)

14-Feb-08

D. Protti - University of Victoria and City

University London

57

In the past…

But now…

Very few pharmacies were directly connected to

physician practices

Over 95% of US pharmacies are connected into

a single network and growing

Electronic communications meant faxes

Computer applications can communicate directly

with each other

Only half the problem was being addressed…

writing new scripts

Renewals can be automated in addition to new

scripts

Software didn’t support the workflows in the

practice

Software integrates with existing practice

systems and smoothes office workflow

There were few real benefits for most practices

Most practices will save physician and staff time

as well as improve patient safety

There wasn’t a future path to additional benefits

Collaborate with pharmacies and payors on

patient compliance and other future functions

Automation was being driven by a few Health

Plans and small software vendors

State and nation-wide initiatives involving all

major stakeholders

(58)

14-Feb-08 D. Protti - University of Victoria and City University London

58



Cost of buying, installing and supporting a system



Lack of reimbursement for costs and resources



Increased time to use the system = reduced

productivity (initially)



Time required to review warnings, alerts and

recommendations

(59)

14-Feb-08

D. Protti - University of Victoria and

City University London

59

Barriers

• State regulations are not a barrier

• Electronic signatures are not a barrier

• The biggest barrier or hindrance to electronic

prescribing is educating the prescribers to the

benefits of electronic prescribing and pharmacy

readiness

– Think electronic prescribing is just New Rxs

– Are not aware of the significant ROI for automating

refill authorizations

References

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