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The SPLUNC1-βENaC complex prevents Burkholderia cenocepacia invasion in normal airway epithelia

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Figure

Fig. 1 SPLUNC1 knockout mice have increased susceptibility to J2315 infection. Male and female SPLUNC1 −/− and wild-type littermate mice were infected intratracheally with 5 × 10 7 CFU/mouse J2315
Fig. 3 The plasma membrane SPLUNC1- βENaC complex protects cells from B. cenocepacia invasion
Fig. 4 CF HBECs have reduced SPLUNC1 at plasma membrane and increased J2315 burden. Normal and CF HBECs were pre-treated with 10 μM rSPLUNC1-DyLight633 for 3 h

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