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CD122 blockade restores immunological tolerance in autoimmune type 1 diabetes via multiple mechanisms

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Figure

Figure 1. Anti-CD122 treatment suppresses insulitis and diabetes in NOD mice. (shown as mean ± SEM
Figure 2. CD122 expression in various immune cells. (A) The expression profile of Cd122 in representative immune cell populations from the ImmGen (www.immgen.org)
Figure 3. The phosphorylation of STAT5 in NK and T cells.
Figure 4. Anti-CD122 treatment alters immune compartment in pancreatic islets. (plots (left) and statistics (right) of Tregs from pancreatic islets of mice as in cells as indicated from mice as in PA) Representative FACS plots of immune cell profiles in pa
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