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Animal experimental research design in critical care

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Figure

Fig. 1 Study flow diagram
Fig. 2 Frequencies of recommended study design feature reportingper journal. Comparison was made using Chi square test
Table 1 Reporting of recommended study design features in critical care medicine manuscripts 2005 and 2015 (binary ratings).Comparisons were made using Chi square tests (P-value) and simple logistic regression (odds ratio)
Table 3 Inter-rater agreement for binary ratings of metrics using Cohen’s Kappa, Gwet’s AC1, and observed agreement

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