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The antidepressant effects of GM-CSF are mediated by the reduction of TLR4/NF-ĸB-induced IDO expression

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Figure

Fig. 1 Comparison of the forced swim test results between study groups. For LPS treatment, 1 indicates administration while 0 indicates nointeraction with LPS administration (fluoxetine (significant following fluoxetine treatment regardless of LPS administ
Fig. 2 Comparison of IDO mRNA and protein expression between study groups. The LPS + GM-CSF group were pretreated with GM-CSF (30 μgkg, i.p.) 30 min prior to LPS injection (0.83 mg/kg, i.p.)
Fig. 3 (See legend on next page.)
Fig. 4 Schematic representation of the mechanism underlying the antidepressant effects of GM-CSF

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