Magnetic Resonance Techniques
in Multiple Sclerosis
Eighteenth Advanced Course
SCIENTIFIC PROGRAM
CME ACCREDITED COURSE
Milan, 19-20 March 2015
San Raffaele Scientific Institute Via Olgettina, 60 - 20132 Milano, Italy
Neuroimaging Research Unit
Institute of Experimental Neurology, Division of Neuroscience,
San Raffaele Scientific Institute and Vita - Salute San Raffaele University
Università Vita-SaluteORGANIZING SECRETARIAT
Biomedia srl – Monica Arosio Via L. Temolo 4 – 20126 Milano Tel. 02/45498282 - Fax 02/45498199
Magnetic Resonance Techniques in Multiple Sclerosis - Eighteenth Advanced Course
Milan, 19-20 March 2015 1
Maria P. Amato (Firenze, Italy) John Ashburner (London, UK) Marco Battaglini (Siena, Italy) Ralph Benedict (Buffalo, USA) Giancarlo Comi (Milan, Italy) John De Luca (West Orange, USA)
Nicola De Stefano (Siena, Italy) Christian Enzinger (Graz, Austria)
Arman Eshaghi (Teheran, Iran) Monica Falautano (Milan, Italy)
Massimo Filippi (Milan, Italy) Jeroen J. Geurts (Amsterdam, Netherlands)
Roland Henry (San Francisco, USA) Mark A. Horsfield (Leicester, UK)
Mark Jenkinson (Oxford, UK) Carsten Lukas (Bochum, Germany)
Maria A. Rocca (Milan, Italy) James Sumowski (West Orange, USA)
Koen Van Leemput (Boston, USA) Alex P. Zijdenbos (Montreal, Canada)
FACULTY MEMBERS
MAGNETIC RESONANCE TECHNIQUES
IN MULTIPLE SCLEROSIS
Eighteenth Advanced Course Milan, 19-20 March 2015 SCIENTIFIC DIRECTION: M. Filippi G. Comi SCIENTIFIC SECRETARIAT: M.A. Rocca ORGANIZING SECRETARIAT: G. Nyitrai L. Zonca
Programme
19 March 2015
09.00-09.15 Welcome, introductory remarks
G. Comi
09.15-09.30 Program overview
M. Filippi
Atrophy quantification in MS: from clinical needs to methodological pitfalls. Towards the identification of the best method?
SESSION I - THE CLINICAL PERSPECTIVE
Chairs: M. Filippi, G. Comi
09.30-10.00 What structures should be measured? Whole brain vs WM/GM segmentation?
N. De Stefano
10.00-10.30 Deep GM nuclei: a simple, clinically meaningful measure?
R. Benedict
10.30-11.00 Spinal cord atrophy: the missing measure?
C. Lukas
11.00-11.30 Coffee break
SESSION II - METHODOLOGICAL CONSIDERATIONS
Chairs: N. De Stefano, R. Henry
11.30-12.00 How to measure: accuracy, reproducibility, sensitivity to changes
M.A. Horsfield
12.00-12.30 T1 lesion refilling: how and why?
M. Battaglini
Magnetic Resonance Techniques in Multiple Sclerosis - Eighteenth Advanced Course
Milan, 19-20 March 2015 3
Programme
SESSION III - METHODS AND SOFTWARES: CROSS-SECTIONAL AND LONGITUDINAL APPLICATIONS, PROS AND CONS I
Chairs: M.A. Rocca, A. Eshaghi
13.30-14.00 FSL: SIENA, SIENAx, FIRST
M. Jenkinson 14.00-14.30 SPM J. Ashburner 14.30-15.00 Freesurfer K.V. Leemput 15.00-15.30 Afternoon tea
SESSION IV - METHODS AND SOFTWARES: CROSS-SECTIONAL AND LONGITUDINAL APPLICATIONS, PROS AND CONS II
Chairs: R. Benedict, M.A. Horsfield
15.30-16.00 CIVET
A.P. Zijdenbos
16.00-16.30 ANTs
A. Eshaghi
16.30-17.00 How to choose a method and its implementation
R. Henry
17.00-18.00 SESSION V - ROUND TABLE SUMMING UP AND CONCLUSIONS
Chair: M. Filippi
Discussants: N. De Stefano, R. Benedict, C. Lukas, M.A. Horsfield, R. Henry
20 March 2015
Imaging cognitive dysfunction in MS
SESSION VI - THE CLINICAL PERSPECTIVE
Chairs: M. Falautano, J. Sumowski
9.00-9.15 Introduction
G. Comi
9.15-9.45 Neuropsychological profiles in MS: from cognitive relapse to dementia
J. De Luca
9.45-10.15 Cognitive assessment: towards a unified evaluation
M.P. Amato
10.15-10.45 Coffee break
SESSION VII - THE IMAGING PERSPECTIVE
Chairs: J. De Luca, M.P. Amato
10.45-11.15 WM lesions and damage: just a disconnection syndrome?
C. Enzinger
11.15-11.45 GM lesions and damage: do they explain the whole story?
J.J. Geurts
11.45-12.15 Plasticity: what is the evidence?
M.A. Rocca
12.15-12.45 Brain reserve and cognitive reserve: where are we going?
J. Sumowski
12.45-13.15 Concluding remarks
M. Filippi
13.15-14.30 Farewell cocktail
Magnetic Resonance Techniques in Multiple Sclerosis - Eighteenth Advanced Course
Milan, 19-20 March 2015 5
General Information
REGISTRATIONRegistration is free and includes admission to scientific sessions, conference materials, coffee breaks, lunch and certificate of attendance.
HOW TO REGISTER
All participants are kindly recommended to register via the online registration form at www.biome-dia.net
CONTINUING MEDICAL EDUCATION (ECM only for Italian participants)
The event addresses to the disciplines of Neurology, Neurophysiopathology, Neuroradiology. In order to obtain credits, participants must attend the full educational programme (100% of the meeting) and pass the final learning test available on line on the site www.providerecm.it.
CERTIFICATE OF ATTENDANCE
A certificate of attendance will be available to each participant at the end of the meeting
OFFICIAL LANGUAGE
English. Simultaneous translation service is not provided.
HOTEL ACCOMMODATION
In case of accomodation please contact: Biomedia Travel di Biomedia srl Via L. Temolo, 4 – 20126 Milano
Tel.: 02/45498282 - Fax: 02/45498199 - e-mail: biomediatravel@biomedia.net
CONGRESS VENUE
San Raffaele Scientific Institute - Aula San Raffaele (c/o Direzione Sanitaria) Via Olgettina, 60 - 20132 Milano, Italy
HOW TO REACH THE VENUE
Motorways: San Raffaele Congress Centre can be reached by all motorways, following the direc-tion "Tangenziale Est" (East ring road) till Cascina Gobba exit.
Subway: San Raffaele Congress Centre is connected to Milan by green subway line. The subway stop is Cascina Gobba.
Railway: Milano Central Railway Station is connected to San Raffaele Congress Centre by subway (green line).
Airports: Malpensa Airport (50 km) and Linate Airport (5km) are connected to San Raffaele Congress Centre by railway, bus or taxi.
