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The Exon Junction Complex and Srp54 Contribute to Hedgehog Signaling via ci RNA Splicing in Drosophila melanogaster

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Academic year: 2020

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Figure 1 Screen for Hh pathway modiSrp54 RNAiUAS-Srp54 RNAipercentage of controls for discs expressingthe AP axis (anterior to the left of zero) of the wing pouch for four wing discs in a single experiment, comparing (M) to control (both also express mago
Figure 2 Different effects of Mago and Srp54 inhibition on Ci-155 levels and activity
Figure 3 Mago and Srp54 regulate ci RNA. (A) Schematic representation ofci-A and ci-B RNAs, together with primer locations (exons are boxed withtranslated segments in orange)
Figure 4 Cell autonomous action of EJC members and Srp54 on Hh pathway activity. (A) Homozygousrelative to controls within (L and M)greatly byStudentclones, (N)ptc-lacZbackground, marked by loss of GFP (green), had lower Ci-155 levels [white, (Astaining [b
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