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Transportan in nanocarriers improves skin localization and antitumor activity of paclitaxel

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Figure

Table 1 characteristics of the microemulsions
Figure 2 rate of paclitaxel penetration into the skin.Note: Data presented as average ± sD of three to seven replicates.Abbreviations: sc, stratum corneum; h, hours; eD, viable epidermis and dermis; Me, microemulsion; Me-P, microemulsion containing penetratin; Me-T, microemulsion containing transportan; Me-TaT, microemulsion containing TaT; sD, standard deviation.
Figure 5 Irritation potential of PTD-containing formulations.Notes: (A) depicts viability of tissues after 2–15 hours of treatment with the formulations compared to PBS and Triton; (B) depicts the comparison of extracellular Il-1α levels
Figure 6 effect of paclitaxel in solution or incorporated in Me-T on the viability of basal cell carcinoma cells.Note: *P,0.05 compared to the drug solution in propylene glycol.Abbreviation: Me-T, microemulsion containing transportan.

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