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Original Article microRNA-22 alleviates murine lupus nephritis by targeting NLRP3

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Figure

Figure 1. NLRP3 inflammasome activation in MRL/lpr mice. A, B. Detection of NLRP3, ASC, and caspase-1 p20 by western blot
Figure 3. Serum anti-dsDNA antibody level and renal immune complex de-position. A. By ELISA, serum anti-dsDNA antibody was assessed
Figure 5. Bioinformatics analysis of the targets of miR-22 and luciferase reports. The luciferase reporter vector containing WT NLRP3-3’-UTR or mutant 3’-UTR was cotransfected with miR-22 or control into HEK293 cells

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