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The emerging roles of exosomes in leukemogeneis

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Academic year: 2020

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Figure

figure 1: biogenesis of exosomes. A. An endosome forms from invagination of the plasma membrane to surround macromolecules or other cargos within the extracellular environment
figure 2: summary of role of exosomes in leukemogenesis. Leukemia-derived exosomes can activate bone marrow stromal cells (BMSCs) to promote leukemia cell survival, proliferation and resistance to chemotherapy
figure 3: process of dendritic cell-based leukemia immunotherapy using leukemia cell-derived exosomes as the source of antigens

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