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Inhibition of cyclin dependent kinase 9 by dinaciclib suppresses cyclin B1 expression and tumor growth in triple negative breast cancer

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Figure

Figure 1: Dinaciclib inhibits cell proliferation of TNBC more effectively than that of ER+ breast cancer
Figure 2: Dinaciclib induced apoptosis in TNBC from PDXs and cell lines. A. and B. FACS analysis of TNBC cells from PDXs (WHIM3 and WHIM12) and cell lines (BT549, HCC1806, MDA-MB-231) treated with dinaciclib for 24 hours
Figure 3: Dinaciclib promotes G2/M phase arrest in TNBC from PDXs and cell lines. A, B, C, D
Figure 4: CDK1 or cyclin B1 knockdown inhibited cell proliferation, induced apoptosis and G2/M arrest in TNBC cells.and cyclin B1 knockdown on cell proliferation by Alamar Blue cytotoxic assay  A
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