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Cyclical expression of GDNF is required for spermatogonial stem cell homeostasis

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Figure

Fig. 1. Stage-specific expression of GDNFincreases the Adensity of GFRA1PCR on seminiferous tubule RNA, staged bytransillumination (Fig
Fig. 2. GDNF increases SSC-specificgene expression and enhancesTg(Gdnf)GFRA1 and THY1.2 fractions, but notthe KIT fraction
Fig. 3. GDNF does not change spermatogoniaproliferation.1 day after BrdU injection. While 27% of GFRA1cluster
Fig. 4. PLZF+ cells recover more slowly following
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