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NRF2 promotes neuronal survival in neurodegeneration and acute nerve damage

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Figure

Figure 1. Expression of endogenous antioxidative enzymes in mouse photoreceptors. (A) Schematic illustration of rod and cone death kinetics of the 3 RP mouse models used in this study
Figure 2. Cones express a high level of GFP from an AAV8 with a CMV promoter. (A) Dissected retinae were imaged for GFP fluorescence (green) driven by AAV-GFP, following infection at P0 and imaging at P30
Figure 3. SOD2 and catalase effects on cone survival. (A) Schematics of AAV-GFP and AAV-SOD2-2A-CAT constructs
Figure 4. Effects of antioxidative TFs on cone survival. ((A) Schematics of AAV-PGC1a and AAV-NRF2 constructs
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