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A novel anti-GD2/4-1BB chimeric antigen receptor triggers neuroblastoma cell killing

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Academic year: 2020

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Figure

Figure 1: T cells are effectively transduced with GD2 CAR encoding vector. A. The GD2 CAR construct
Figure 2: Effectors characterization. A. non-transduced T cells (NT), GFP only T cells and GD2 CAR T cell sub-populations assessed by flow cytometry: both GFP only T cells and GD2 CAR T cell population was mainly constituted by CD3+/CD8+ cells as well as C
Figure 4: GD2 CAR T cells exert specific in vitro cytotoxicity. A. 4-hour standard 51Cr release assay
Figure 5: GD2 CAR T cells provide potent therapeutic activity in a neuroblastoma xenograft

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