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DeepCpG: accurate prediction of single cell DNA methylation states using deep learning

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Figure

Fig. 1 DeepCpG model training and applications. a Sparse single-cell CpG profiles as obtained from scBS-seq [5] or scRRBS-seq [6–8]
Fig. 2 DeepCpG accurately predicts single-cell CpG methylation states.using additional annotations from corresponding cell types (at a single CpG site (methylation features (performance on 12 2i-grown mESCs profiled using scBS-seq [5], as well as three cel
Fig. 3 Discovered sequence motifs associated with DNA methylation. Clustering of 128 motifs discovered by DeepCpG
Fig. 4 Effect of single-nucleotide mutations on DNA methylation. Average genome-wide effect of single-nucleotide mutations on DNA methylationestimated using DeepCpG, depending on the distance to the CpG site and genomic context
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