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Paget’s disease derived in situ from reserve cell hyperplasia, squamous metaplasia, and squamous cell carcinoma of the esophagogastric junction: a case report

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Figure

Fig. 1 Endoscopy and FDG-PET/CT findings. a, b Endoscopy findings, showing a mild granular elevated lesion with slightly depressed irregularmucosa extending from the anterior wall to the right wall of the distal esophagus (arrowheads)
Fig. 2 Surgically resected specimen of the lesions in the esophagusand proximal stomach
Fig. 3 Microscopic findings. a Hematoxylin and eosin staining of a tumor section, showing neoplastic cells (Paget cells) with a large nucleus anda pale-staining cytoplasm in the lower part of the esophageal epithelium
Table 1 Result of histochemical and immunohisotochemicalexaminations in Paget cell and squamous cell carcinoma (SCC)components

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