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Promoter DNA Methylation of DNA Repair Genes in Cancer

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Figure 2: Repression of transcription via CpG dinucleotide methylation.Adapted from Ref 16
Figure 3: Methylation precipitating a point mutation. Adapted from Ref 11. Cytosine to thymine point mutation after deamination of methylated cytosine.
Table 1. Epigenetic Aberrations among Different Tumor Types.
Figure 5: Hypermethylation profile of promoter region CpG island of tumor suppressor genes in human cancer.Adapted from Ref 21
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