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PBX proteins: much more than Hox cofactors

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Figure

Fig. 2. Pbx is at the crossroads of several signaling pathways. Pbx is able to integratewith specific transcription factors and chromatin-remodeling enzymes and contributes to thehedgehog and Notch signaling
Fig. 3. Pbx proteins have a major role in integrating cell signaling andtriggering subsequent developmental genetic programsoverall complex interaction with the basal transcriptional machinery.transcription factors

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