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A lipid-rich gestational diet predisposes offspring to nonalcoholic fatty liver disease: a potential sequence of events

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Figure

Figure 1 Generalized pathway of lipid metabolism. Notes: Cytoplasmic nonesterified fatty acids are rapidly converted to fatty acyl-CoA, which may proceed to undergo β-oxidation or serve as a substrate for either TAG or phospholipid synthesis
Figure 2 The methionine cycle and transsulfuration pathway.Notes: Glutathione synthesis begins with the conversion of homocysteine into cystathionine, which is dependent on the presence of both serine and cystathionine β-synthase
Figure 3 Sequence of physiological changes resulting from a maternal lipid-rich diet. Notes: The left cycle demonstrates how NEFA activation and packaging by the ER results in ER stress, which then spurs the activation of fatty acid synthesis – as part of

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