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Growth and pattern of the mammalian neural tube are governed by partially overlapping feedback activities of the hedgehog antagonists patched 1 and Hhip1

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Figure

Fig. 1. External features of E10.5 embryos with reduced feedbackLDA to Hh signaling. Genotypes are indicated in each panel.
Fig. 2. Growth and patterning phenotypes of (T) Quantification of the size of each progenitor domain along the DV axis in celldiameters in wild-type, tube at E10.5
Fig. 3. Patterning phenotypes of the MtPtch1;Ptch1MtPtch1;Ptch1domain. (a) Representation of the size of each progenitor domain along the DV axis as apercentage of the total DV length of the neural tube
Fig. 4. Changes in ventral anddorsal neuronal precursor
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