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Reassignment of specificities of two cap methyltransferase domains in the reovirus lambda2 protein

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Figure

Figure 1Stereoview ribbon diagrams of superimposed structures of the MTase 1 domain (green), VP39 (blue) and RrmJ (magenta).MTase 1 shows elaborations of the common fold similar to those of VP39, which are altogether absent from the RrmJstructure and which
Figure 2Sequence alignment of the predicted human reovirus cap 1 MTase with its counterpart from grass carp reovirus (GCRV) andvaccinia virus (VP39)
Figure 3Stereoview of superimposed structures of the MTase 1 domain (ribbon in green, side chains and labels in red) and VP39(ribbon and labels in blue, side chains in cyan), delineating the proposed binding sites for the guanine moiety and the targetribos
Figure 5Sequence alignment of the MTase 2 domain with its counterpart from grass carp reovirus

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