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DotAligner: identification and clustering of RNA structure motifs

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Figure

Fig. 1 Schematic of a pairwise alignment with DotAligner. A dynamic programming matrix is first filled in based on the similarity in sequence andcumulative base-wise pairing probabilities of two RNA sequences (top left: colour intensity indicates cumulativ
Fig. 2 Comparison of RNA structure alignment quality as a function of sequence identity
Figure S4).The efficacy of the heuristics implemented in DotAl-igner is further accentuated by its runtime, which con-sistently lies between simple sequence alignment andmore sophisticated RNA structure alignment algorithms(Fig
Table 1 Comparative clustering performance
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