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FOCS: a novel method for analyzing enhancer and gene activity patterns infers an extensive enhancer–promoter map

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Figure

Fig. 1 FOCS statistical procedure for inference of Eand promoters that passed the validation tests (FDRclosest enhancers (the dependent variables)
Fig. 2 Performance of three alternative regression methods for inferring Eon a plot indicates that a fraction x of the models had–P models
Fig. 3 Configuration of promoter regulation by enhancers. a The proportional contributions of the ten most proximal enhancers (within ±500 kbof the target promoter) to models predicting promoter activity
Table 1 Number of inferred promoter models obtained by four alternative methods on the ENCODE DHS dataset
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