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Comparison of a healthy miRNome with melanoma patient miRNomes: are microRNAs suitable serum biomarkers for cancer?

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Academic year: 2020

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Figure

Figure 1: Overview of study design. Numbers in brackets indicate number of separate samples included in pools
Figure 2: the secreted healthy mirNome. A) Stability of the healthy miRNome. Mean-standard deviation plots of averaged raw Cq values or normalized expression for 1066 miRNAs (qPCR arrays of 3 serum pools (from 19 individual healthy donors) and circadian se
Figure 4: biomarker studies. A) Heatmap and PCA showing the averages of samples belonging to different melanoma stages and healthy serum samples (based on Fig
Figure 5: comparison of tissue and serum samples. Bar diagram showing averaged relative expression values from available serum (blue), normal skin (red), primary tumour lesion (green) and metastatic lesions (purple) samples

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