DECODE them. Now you can do more than treat their allergies. You can

(1)

Before you treat it, ImmunoCAP it.

Now you can do more than

treat

their allergies.

You can

DECODE

them.

ImmunoCAP Specifi c IgE blood test gives you results on a panel of allergens tailored to your

patients’ specifi c region to optimize your diagnosis and treatment of allergic rhinitis (AR) this year.

Before you treat it, ImmunoCAP it. Visit decodeallergies.com/physicians

The key to keeping patients symptom-free is understanding your patients’

allergic symptom threshold. With ImmunoCAP, you can effectively manage and treat,

or refer your patients.

• Find out if patients’ symptoms are allergic or non-allergic

• Manage and treat your patients’ allergic symptom threshold

• Prevent unnecessary medications and unscheduled doctor visits

• Reduce costs associated with absenteeism and lost productivity at work or school

Thermo Fisher Scientifi c

4169 Commercial Avenue, Portage, MI 49002, 800.346.4364, www.thermoscientifi c.com/phadia 549539.03

All trademarks are the property of Thermo Fisher Scientifi c Inc., and its subsidiaries Legal Manufacturer: Phadia AB, Uppsala, Sweden

References

1. Tran NP, Vickery J, Blaiss MS. Management of Rhinitis: allergic and non-allergic. Allergy Asthma Immunol Res. 2011;3(3):148-156. 2. Szeinbach SL, Williams B,

Muntendam P, et al. Identifi cation of allergic disease among users of antihistamines. J Manag Care Pharm. 2004;10(3):234-238. 3. Asthma Allergy Foundation of America. Web site: accessed November 1, 2012. http://www.aafa.org/display.cfm?id=9&sub=18&cont=239. 4. American College of Allergy, Asthma & Immunology. Web site: accessed November 6, 2012. http://www.acaai.org/allergist/allergies/types/rhinitis/Pages/default.aspx 5. Ciprandi G, Alesina R, Ariano R, et al. Characteristics of patients with allergic polysensitization; the polismail study. Eur Ann Allergy Clin Immunol. 40(3); 2008: 77-83. 6. Sin B, Togias A. Pathophysiology of allergic and nonallergic rhinitis. Proc Am Thorac Soc. 2011; 8(1):106-114. 7. Zethraeus N, Peterson CJ, Dozzi M, et al. Health care cost reduction resulting from primary care allergy testing in children in Italy. Journal of Pediatrics. 2010;36:1-7. 8. Cox L, William B, Sicherer S, et al. Pearls and pitfalls of allergy diagnostic testing: report from the American College of Allergy, Asthma and Immunology/American Academy of Allergy, Asthma and Immunology Specifi c IgE Test Task Force. Ann Allergy Asthma Immunol. 2008;101:580-592. 9. Wang J, Godbold JH, Sampson HA. Correlation of serum allergy (IgE) tests performed by different assay systems. J Allergy Clin Immunol. 2008;1219-1224. 10. Johansson SG. ImmunoCAP specifi c immunoglobulin E test: tool for research and allergy diagnosis. Expert Rev Mol Diag. 4(3). 2004:89-95.

11. Kwong KYC, Eghrari-Sabet JS, Mendoza GR, et al. The benefi ts of specifi c Immunoglobulin e testing in the primary care setting. Am Manag Care. 2011;17:S447-S459. 12. National Institutes of Health. Web site: accessed November 6, 2012: http://www.nlm.nih.gov/medlineplus/ency/article/000814.htm. 13. Le Bras M, Jones SM.

Inner City Asthma Study: relationships among sensitivity, allergen exposure, and asthma morbidity. Pediatrics. 2006;118:S11-S12. 14. National Heart Lung and Blood Institute. National Asthma Education and Prevention Program. Expert Panel Report 3: Guidelines for the Diagnosis and Management of Asthma. Full Report 2007. US Department of Health and Human Services. National Institutes of Health. National Heart Lung and Blood Institute. 15. Allen-Ramey F, Schoenwetter WF, Weiss TW, et al. Sensitization to common allergens in adults with asthma. J Am Board Fam Pract. 2005;18(5):434-439. 16. Host A, Halken S. The role of allergy in childhood asthma. Allergy. 2000;55:600-608.

You can do more than

treat

their allergies.

Now you can

DECODE

them.

11 Befor

e ImmunoCAP, spring and f

all wer

e especially difﬁ

cult.

oms.

ergic sympt

erbated by her all

thma was exac

Sophie’s as

After ImmunoC

AP, Sophie is breathing easier y

ear-round.

e kept her under her

autionary measures hav

ation and prec

New medic

aller

gic symptom thr

eshold.

Better management s

tarts with kno

wing.

en their symptoms ar

y alike, but oft

e exactl

No two patients ar

e similar .

ant than ever

gy, it's more import

thma and aller

With rising incidences of as

to dec

ode your patients' sympt

oms and know the r

eal cause behind their disc

omfort.

JAN FEB MAR

APR MAY JUN

JUL AUG

SEP

OCT

NOV DEC

JAN FEB MAR

APR MAY JUN

JUL AUG SEP OCT NOV DEC Cockr oach ( 19.48 kUA/L ) Ragweed ( 20.02 kUA/L ) SYMPT OM THRESHOLD Oak tree (23.56 kU A/L ) Ragweed SYMPT OM THRESHOLD Sympt oms contr olled Oak tree Cockr oach

(2)

Similar symptoms—different causes.

2

Clinical history is not enough. With such a costly condition, ImmunoCAP can help you make sure

they have the right medication.

According to the Asthma and Allergy Foundation of America,

3

types of rhinitis include:

Nearly 2/3 of patients prescribed

antihistamines for their reported

allergic rhinitis have symptoms

that are not

due to allergy*

*Study of 1-year managed care records among 4,643 patients who received 1 or more prescriptions for an oral antihistamine (loratadine, fexofenadine, or cetirizine).

INFECTIOUS RHINITIS

NON-ALLERGIC RHINITIS

Infectious rhinitis could be bacterial

or viral. Usually short term but

symptoms may be indistinguishable

from those of other causes.

Perennial/chronic in nature, can

also follow exposure to irritants,

eg: smoke, aerosol sprays, exhaust

fumes, fragrances, paint fumes, and

air pollution.

4

Seasonal—Is a reaction to pollen

from trees and grasses. Occurs

mainly in the spring and fall, when

pollens from trees, grasses, and

weeds are airborne.

Perennial—Caused by sensitivities

that are present throughout the

year, such as dust mites, mold,

pet dander, or cockroach residue.

ALLERGIC RHINITIS

*Study of 1-year managed care records among 4,643 patients who received 1 or more prescriptions for an oral

35 %

65 %

ALLERGIC

RHINITIS

NON-ALLERGIC

RHINITIS

Why you need to

decode

what they’re saying

The biggest symptom is the impact on their lives

.

Allergic rhinitis is the

5th costliest

chronic condition in the US in overall costs.

1

ALEX’S PARENTS REPORT:

Runny nose

Itchy, watery eyes

Sneezing

5 missed school days

BRIAN REPORTS:

Nasal congestion

Sneezing

Headache due to occasional

cold symptoms

Not feeling up to exercising

NATALIE REPORTS:

Nasal congestion

Cough

Feels like I’m

(3)

decode

his symptom threshold

Now he knows exactly where his symptoms are coming from.

Brian’s doctor recommended a multifaceted approach of medication and exposure

reduction to manage his condition.

90 %

of allergy

patients are actually

multisensitized

(sensitized to two or

more allergens)

5

decode

his symptom threshold

For most AR patients, the causes are cumulative.

The allergic symptom threshold is the level at which a patient’s allergic sensitivities cause

symptoms. A patient’s threshold is often exceeded when spring allergens and perennial

allergens add up to create a cumulative effect.

Previously unknown high

sensitivity to dust mites

present year-round

Increase in birch

pollen in spring pushes

patient over threshold

Increase in ragweed

pollen in the fall is enough

to cause sneezing and

watery eyes

JAN FEB MAR APR MAY JUN JUL AUG SEP OCT NOV DEC

Dust mite (19.18 kUA/L) Mold (12.09 kUA/L)

Ragweed (11.73 kUA/L)

SYMPTOM THRESHOLD

Birch pollen (32.31 kUA/L)

· Previous exposure to allergic triggers can lead to “priming,”

which creates a higher likelihood of hyperresponsiveness

upon repeated exposures

6

· Managing patients’ symptoms is about knowing all of their

IgE sensitivities —even the ones that are hidden

· ImmunoCAP testing has been shown to decrease the expected

cost of allergy treatment by

43%

7

(4)

decode

to optimize management

ImmunoCAP is the most widely used speciﬁ c IgE test in the US

among healthcare professionals, including specialists.

8,9

A recent Journal of Allergy and Clinical Immunology study supports ImmunoCAP as the

standard in quantitative IgE testing and recommends against using different assays after

initiating with ImmunoCAP.

9

_{Accepted by most managed care plans nationwide.}

Now you and your

patients can manage

the real causes

associated with AR

symptoms.

<0.35 <0.35 <<0.35 <0.35 <<0.35 <<0.35 <0.35 <0.35 <0.35 LAB SERVICES

decode

to optimize management

Clear results are easy to interpret and explain to patients.

Quantifi able levels of allergen antibodies (IgE) down to the kilounit (kUA/L).

Sample Test Results

· CONVENIENT: Results come back in a week or less, similar to a lipid

panel test; simple blood draw; can be drawn in the offi ce or at any lab

· COMPREHENSIVE: Reports sensitivities with a customized panel of

aeroallergens tailored to your region

· SENSITIVE: Third-generation specifi c IgE blood test detects AR in

up to 95% of patients

10

_;

signifi cantly more sensitive than RAST

0.94 6.87 1.22 20.01 23.55 1.23 1.23 0.00-0.35 kU/L 0.70-3.49 kU/L 0.00-0.35 kU/L 0.70-30.00-0.35 kU/L 0.00-0.35 kU/L 0.00-0.35 kU/L 0.00-0.35 kU/L 3.50-17.49 kU/L 0.70-3.49 kU/L 17.50-49.99 kU/L 0.00-0.35 kU/L 17.50-49.99 kU/L 0.00-0.35 kU/L 0.00-0.35 kU/L 0.70-3.49 kU/L Maple Tree IgE

Elm Tree IgE Oak Tree IgE Ash Tree (White) IgE Birch Tree IgE Alternaria tenuis IgE Timothy Grass IgE Johnson Grass IgE Bermuda Grass IgE Rye Grass IgE

June/Kentucky Blue IgE Ragweed (common) IgE Orchard Grass IgE Cockroach Dust mite <0.35 <0.35 <<0.35 <0.35 <<0.35 <<0.35 <0.35 <0.35 <0.35 LAB SERVICES 0.94 6.87 1.22 20.01 23.55 1.23 1.23 1.23 0.00-0.35 kU/L 0.70-3.49 kU/L 0.00-0.35 kU/L 0.70-30.00-0.35 kU/L 0.00-0.35 kU/L 0.00-0.35 kU/L 0.00-0.35 kU/L 3.50-17.49 kU/L 0.70-3.49 kU/L 17.50-49.99 kU/L 0.00-0.35 kU/L 17.50-49.99 kU/L 0.00-0.35 kU/L 0.00-0.35 kU/L 0.70-3.49 kU/L Maple Tree IgE

Elm Tree IgE Oak Tree IgE Ash Tree (White) IgE Birch Tree IgE Alternaria tenuis IgE Timothy Grass IgE Johnson Grass IgE Bermuda Grass IgE Rye Grass IgE

June/Kentucky Blue IgE Ragweed (common) IgE Orchard Grass IgE Cockroach Dust mite

IgE CLASS CONCENTRATION (kUA/L)

0 <0.35 Below detectable limits I 0.35-0.69 Low II 0.70-3.49 Moderate III 3.50-17.49 High IV 17.50-49.99 Very High V 50.00-99.99 Very High VI =/>100 Very High SPECIMEN INFORMATION SPECIMEN: REQUISITION: COLLECTED: 10/30/12 REPORTED: 10/30/12 AMENDED: REPRINTED: ORDERING PHYSICIAN JONES, S. CLIENT INFORMATION 7200

NEW YORK LABS.

123 MAIN ST. Suite 1100 NEW YORK, NY 12345

(5)

AR-seasonal/perennial

Maple, birch pollen, dust mites

Their allergies, fi nally

decoded

Alex had allergy-like symptoms.

He was taking an antihistamine

and an intranasal steroid (INS).

Alex’s physician discontinued

antihistamines and told his mom

to stop using a chemical carpet

freshener that was irritating his

eyes and throat.

· Mom no longer using same

carpet freshener

· Continues INS when needed

· Mom saves money by eliminating

unnecessary antihistamine

11

alex

back on

the bus

exercising

again

Non-allergic rhinitis

No allergies revealed

Now only taking antihistamines

during allergy season.

· Use of allergen-impermeable

pillow case covers has

substantially cut his exposure

to dust mite triggers

12

brian

Natalie loves cats but ImmunoCAP

revealed a 34.1 (very high) IgE sensitivity

to mold and 3.6 (low) sensitivity to cat

· Dehumidifying home to reduce mold

· Keeping her cat, just not in the bedroom

· Taking antihistamine when necessary

natalie

feline

friendly

AR-perennial/seasonal

Cat dander, ragweed, mold

In one study, patients showed an

average of $255 in savings per year

on unnecessary antihistamines

11

Simple, easy steps to control allergies.

Trigger

tip

Pillow and mattress covers.

Washing bedding in hot water (140

o

_F).

Vacuuming with HEPA fi lter and/or

carpet removal.

Pet-free zones, frequent vacuuming,

HEPA fi lters, fewer pets.

Environmental moisture control, including

use of dehumidifi ers, and avoidance.

Meticulous control of food debris,

as well as use of pesticides or

insecticides when necessary.

Changing clothes and showering

after being outdoors, keeping windows

Dust mites

Pet dander

Mold

Insects

Pollen

(6)

decoding

the allergy/asthma connection

10 Sophie uses an ICS controller for her moderate,

persistent asthma. Recently, swollen nasal passages

and nasal congestion have caused concern.

Now:

AR-asthma

Oak, ragweed, cockroach

sophie

· Up to 69% of children living in

inner city areas with asthma are

sensitized to cockroach

13

· Current NIH guidelines recommend

in vitro

IgE testing as well as

clinical history and physical

exam for all patients with

persistent asthma

14

· 90% of children and 60% of adults

with asthma have allergic triggers

15,16

· Mom has an antihistamine on hand

for when seasonal allergies hit

· A leukotriene receptor antagonist

has helped both her asthma and

allergic symptoms

· Exterminating twice a year whether

or not pests are present

less worry,

more play

Befor

e you tr

eat it, ImmunoC

AP it.

Now y

ou c

an d

o mor

e tha

n

tre

at

th

eir

alle

rgi

es.

You c

an

DECO

DE

th

em

.

ImmunoCAP

Specifi c IgE bl

ood tes

t giv

es you r

esults on a panel of aller

gens tail

ored t

o your

patients’ specifi

c r

egion to optimize y

our diagnosis and treatment of all

ergic rhinitis (AR) this y

ear .

Befor

e you tr

eat it, ImmunoC

AP it. Visit

decodeall

ergies.c

om/physicians

The key t

o keeping patients sympt

om-free is under

standing y

our patients’

alle

rgi

c sympt

om threshold. With

ImmunoCAP

, you c

an effectiv

ely manage and tr

eat,

or ref

er your patients.

• Find out if patients’ sympt

oms are all

ergic or non-all

ergic

• Manage and treat y

our patients’ all

ergic sympt

om threshold

• Prev

ent unneces

sary medications and unschedul

ed doctor visits

• Reduce c

osts as

sociated with absent

eeism and los

t productivity at w

ork or school

4169 Commercial A venue, P

ortage, MI 49002, 800.346.4364, om/phadia 549539.03 c.c www.thermoscientifi

eserved.

All trademarks ar e the property of Thermo Fisher Scientifi

c Inc., and its subsidiaries

Legal Manufactur er: Phadia AB, Uppsala, Sweden

Refer ences

1. T

ran NP, Vick ery J, Blaiss MS. Management of Rhinitis: all

ergic and non-all ergic.

Aller gy Asthma Immunol Res.

2011;3(3):148-156. 2.

Szeinbach SL, Williams B, Asthma All 2004;10(3):234-238. 3. J Manag Care Pharm. s of antihistamines. ergic disease among user cation of all Muntendam P, et al. Identifi ergy F

oundation of gy, Asthma & Immunol ege of Aller American Coll ont=239. 4. g/display.cfm?id=9&sub=18&c .aafa.or sed November 1, 2012. http://www ces eb site: ac America. W ogy. W

eb tics of acteris andi G, Alesina R, Ariano R, et al. Char 5. Cipr ages/default.aspx ergies/types/rhinitis/P gist/all g/aller .acaai.or sed November 6, 2012. http://www ces site: ac patients with aller

gic polysensitization; the polismail s tudy.

Eur Ann Aller gy Clin Immunol. 40(3); 2008: 77-83.

6. Sin B, T

ogias A. Pathophysiol ogy of aller

gic and e aller om primary car eduction resulting fr ost r are c son CJ, Dozzi M, et al. Health c eter Zethraeus N, P 2011; 8(1):106-114. 7. ac Soc. Proc Am Thor gic rhinitis. nonaller gy eport from esting: r gy diagnostic t alls of aller er S, et al. Pearls and pitf Cox L, William B, Sicher 2010;36:1-7. 8. Journal of Pediatrics. aly. ting in children in It tes

the Americ an College of All

ergy, As thma and Immunology/Americ

an Academy of All ergy, As

thma and Immunology Specifi c IgE T

est T ask For ce.

Ann Aller

gy Asthma gy Clin Immunol. J Aller tems. ent assay sys ormed by differ ests perf ergy (IgE) t ang J, Godbold JH, Sampson HA. Correlation of serum all 9. W Immunol. 2008;101:580-592.

2008;1219-1224. 10. Johansson SG. ImmunoC AP specifi c immunogl obulin E tes t: tool f or resear ch and aller gy diagnosis.

Expert Rev Mol Diag.

4(3). 2004:89-95. 2011;17:S447-S459. Am Manag Care. e setting. ting in the primary car obulin e tes c Immunogl ari-Sabet JS, Mendoza GR, et al. The benefi ts of specifi ong KYC, Eghr 11. Kw

12. National Ins titutes of Health. W eb site: ac ces sed November 6, 2012: http://www .nlm.nih.gov/medlineplus/ency/articl e/000814.htm. 13.

Le Bras M, Jones SM. National Heart Lung and Blood 2006;118:S11-S12. 14. Pediatrics. . e, and asthma morbidity gen exposur elationships among sensitivity, aller Inner City Asthma Study: r Institut e. National Asthma Educ

ation and Prev ention Progr

am. Expert Panel Report 3: Guidelines f or the Diagnosis and Management of Asthma. F

ull Report 2007. etter WF, W en-Ramey F, Schoenw 15. All titute. es of Health. National Heart Lung and Blood Ins es. National Institut US Department of Health and Human Servic eiss TW, gy in childhood e of aller en S. The rol Host A, Halk 2005;18(5):434-439. 16. am Pract. J Am Board F gens in adults with asthma. ommon aller et al. Sensitization to c

asthma. Aller gy. 2000;55:600-608.

Now y

ou c

an

DECO

DE

th

em

.

11 Before ImmunoCAP, spring and fall were especially difﬁ cult.

Sophie’s asthma was exacerbated by her allergic symptoms.

After ImmunoCAP, Sophie is breathing easier year-round.

New medication and precautionary measures have kept her under her

allergic symptom threshold.

Better management starts with knowing.

No two patients are exactly alike, but often their symptoms are similar.

With rising incidences of asthma and allergy, it's more important than ever

to decode your patients' symptoms and know the real cause behind their discomfort.

JAN FEB MAR APR MAY JUN JUL AUG SEP OCT NOV DEC

Cockroach (19.48 kUA/L)

Ragweed (20.02 kUA/L)

SYMPTOM THRESHOLD

Oak tree (23.56 kUA/L)

Ragweed

SYMPTOM THRESHOLD Symptoms controlled

Oak tree

ICD 9/CPT Test codes

(7)

Before you treat it, ImmunoCAP it.

Now you can do more than

treat

their allergies.

You can

DECODE

them.

ImmunoCAP Specifi c IgE blood test gives you results on a panel of allergens tailored to your

patients’ specifi c region to optimize your diagnosis and treatment of allergic rhinitis (AR) this year.

Before you treat it, ImmunoCAP it. Visit decodeallergies.com/physicians

The key to keeping patients symptom-free is understanding your patients’

allergic symptom threshold. With ImmunoCAP, you can effectively manage and treat,

or refer your patients.

• Find out if patients’ symptoms are allergic or non-allergic

• Manage and treat your patients’ allergic symptom threshold

• Prevent unnecessary medications and unscheduled doctor visits

• Reduce costs associated with absenteeism and lost productivity at work or school

4169 Commercial Avenue, Portage, MI 49002, 800.346.4364, www.thermoscientifi c.com/phadia 549539.03

All trademarks are the property of Thermo Fisher Scientifi c Inc., and its subsidiaries Legal Manufacturer: Phadia AB, Uppsala, Sweden

References

1. Tran NP, Vickery J, Blaiss MS. Management of Rhinitis: allergic and non-allergic. Allergy Asthma Immunol Res. 2011;3(3):148-156. 2. Szeinbach SL, Williams B,

Muntendam P, et al. Identifi cation of allergic disease among users of antihistamines. J Manag Care Pharm. 2004;10(3):234-238. 3. Asthma Allergy Foundation of America. Web site: accessed November 1, 2012. http://www.aafa.org/display.cfm?id=9&sub=18&cont=239. 4. American College of Allergy, Asthma & Immunology. Web site: accessed November 6, 2012. http://www.acaai.org/allergist/allergies/types/rhinitis/Pages/default.aspx 5. Ciprandi G, Alesina R, Ariano R, et al. Characteristics of patients with allergic polysensitization; the polismail study. Eur Ann Allergy Clin Immunol. 40(3); 2008: 77-83. 6. Sin B, Togias A. Pathophysiology of allergic and nonallergic rhinitis. Proc Am Thorac Soc. 2011; 8(1):106-114. 7. Zethraeus N, Peterson CJ, Dozzi M, et al. Health care cost reduction resulting from primary care allergy testing in children in Italy. Journal of Pediatrics. 2010;36:1-7. 8. Cox L, William B, Sicherer S, et al. Pearls and pitfalls of allergy diagnostic testing: report from the American College of Allergy, Asthma and Immunology/American Academy of Allergy, Asthma and Immunology Specifi c IgE Test Task Force. Ann Allergy Asthma Immunol. 2008;101:580-592. 9. Wang J, Godbold JH, Sampson HA. Correlation of serum allergy (IgE) tests performed by different assay systems. J Allergy Clin Immunol. 2008;1219-1224. 10. Johansson SG. ImmunoCAP specifi c immunoglobulin E test: tool for research and allergy diagnosis. Expert Rev Mol Diag. 4(3). 2004:89-95.

11. Kwong KYC, Eghrari-Sabet JS, Mendoza GR, et al. The benefi ts of specifi c Immunoglobulin e testing in the primary care setting. Am Manag Care. 2011;17:S447-S459. 12. National Institutes of Health. Web site: accessed November 6, 2012: http://www.nlm.nih.gov/medlineplus/ency/article/000814.htm. 13. Le Bras M, Jones SM.

Inner City Asthma Study: relationships among sensitivity, allergen exposure, and asthma morbidity. Pediatrics. 2006;118:S11-S12. 14. National Heart Lung and Blood Institute. National Asthma Education and Prevention Program. Expert Panel Report 3: Guidelines for the Diagnosis and Management of Asthma. Full Report 2007. US Department of Health and Human Services. National Institutes of Health. National Heart Lung and Blood Institute. 15. Allen-Ramey F, Schoenwetter WF, Weiss TW, et al. Sensitization to common allergens in adults with asthma. J Am Board Fam Pract. 2005;18(5):434-439. 16. Host A, Halken S. The role of allergy in childhood asthma. Allergy. 2000;55:600-608.

You can do more than

treat

their allergies.

Now you can

DECODE

them.

11 Befor

e ImmunoCAP, spring and f

all wer

e especially difﬁ

cult.

oms.

ergic sympt

erbated by her all

thma was exac

Sophie’s as

After ImmunoC

AP, Sophie is breathing easier y

ear-round.

e kept her under her

autionary measures hav

ation and prec

New medic

aller

gic symptom thr

eshold.

Better management s

tarts with kno

wing.

en their symptoms ar

y alike, but oft

e exactl

No two patients ar

e similar .

ant than ever

gy, it's more import

thma and aller

With rising incidences of as

to dec

ode your patients' sympt

oms and know the r

eal cause behind their disc

omfort.

JAN FEB MAR

APR MAY JUN

JUL AUG

SEP

OCT

NOV DEC

JAN FEB MAR

APR MAY JUN

JUL AUG SEP OCT NOV DEC Cockr oach ( 19.48 kUA/L ) Ragweed ( 20.02 kUA/L ) SYMPT OM THRESHOLD Oak tree (23.56 kU A/L ) Ragweed SYMPT OM THRESHOLD Sympt oms contr olled Oak tree Cockr oach 549539.02