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Demonstrating functional equivalence of pilot and production scale freeze-drying of BCG

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Figure

Table 1. Freeze-drying protocols as used in this study (PD = primary drying, and SD = secondary drying)
Fig 1. Measured in-process parameters during freeze-drying of BCG at production scale
Fig 2. Effect of the chamber pressure on the average sublimation rate of HGT-medium (black circle), and purified water (clear circle) in the pilot freeze-dryer
Fig 4. Freeze-drying of 10 mL HGT-medium and BCG in HGT-medium in the pilot freeze-dryer

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