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Th17 cells are refractory to senescence and retain robust antitumor activity after long-term ex vivo expansion

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Academic year: 2020

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Figure

Figure 1. High numbers of transferred Th17 cells are required for successful antitumor response
Figure 2. Rapid-expansion protocol (REP) does not improve Th17 yield and reduces antitumor efficacy
Figure 3. Th17 cells expanded for 3 weeks enter quiescence but retain antitumor potency and ability to engraft
Figure 4. Th17 cells are resistant to senescence and apoptosis during ex vivo expansion compared with Th1 cells
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