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Crystal Structures of Human 17β Hydroxysteroid Dehydrogenase Type 1 Complexed with the Dual Site Inhibitor EM 139

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Figure

Table 1. Data collection and refinement statistics.
Figure 2. Stereo representation of the overall structure of A subunit of 17β-HSD1-EM- 139 complex
Figure 3. draw in green and contoured at 1.5σ. The occupancy of the inhibitor was refined to 1
Figure 4. Superposition of A subunit of EM-139 (EM9) binary complex (pink) and E2 steroid binding sites in the superposed structures

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