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Disease driving CD4+ T cell clonotypes persist for decades in celiac disease

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Figure

Figure 1. The number of circulating gluten-specific T cells decreases after commencement of GFD, and the T cell repertoires overlap in samples taken weeks or years apart
Figure 2. Preexisting T cell clonotypes expand and dominate during and (single-cell sequencing
Figure 3. T cell clonotypes persist in gut tissue and blood for decades. Gluten-specific TCR clonotypes observed at various time points in years after commencement of GFD from patients CD412, CD114, and CD373 are depicted in area-proportional Venn diagrams
Figure 4. Public TCR sequences amount to 10% of the gluten-specific T cell repertoire
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