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Optimization of paclitaxel containing pH-sensitive liposomes by 3 factor, 3 level box-behnken design

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Figure

TABLE 1: VARIABLES AND THEIR LEVELS IN BOX-BEHNKEN DESIGN
TABLE 2: BOX-BEHNKEN EXPERIMENTAL DESIGN WITH MEASURED RESPONSES
Fig. 1: Pareto chart.Pareto chart showing the standardized effect of independent
Fig. 4: Contour plot of X2 and X3.Contour plot showing the effect of molar concentration of CHEMS (X2) and amount of drug added (X3) on the percent drug entrapment of liposomes.

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