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Farnesoid X Receptor and Its Ligands Inhibit the Function of Platelets

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Figure

Figure 1 – FXR is expressed in human and mouse platelets. (A) Whole human and mouse
Figure 2 - FXR ligands inhibit platelet activation. Washed human platelets were treated for 5
Figure 3 - The actions of GW4064 on platelets are mediated through FXR. Blood from
Figure 4 – GW4064 inhibits integrin αIIbβ3-mediated outside-in signalling. Effect of GW4064
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