Investor presentation June 2015
Founded in 1990 by CEO Ger van Jeveren
Fagron at a glance
Global market leader active in 32 countries on 6 continents, 2,200 FTE, >300 pharmacists
Share price increased from € 10.25 in 2007 to € 41.50 in 2015
Listed on Euronext Brussels/ Amsterdam
Market cap. of € 1.3 billion
2014: € 447 million of turnover, with REBITDA margin of 26.5%
Proven buy and build strategy, generating margin expansive growth
Global presence
Tampa Trikala Tulsa Uitgeest Waregem Wichita IJsselstein Zeist Kraków Las Vegas Marseille Maryland Heights Medellin Miami Minneapolis Modlniczka Newcastle Oldenzaal Anápolis Arlington Heights Aurora Barcelona Bogotá Bologna Bornem Boom Broken Arrow Cali Cape TownCapelle a/d IJssel Charleroi Copenhagen George Goes Hamburg Helmond Hoogeveen Johannesburg Oud Beijerland Paris Piracicaba Rotterdam Saint-Denis São Paulo Shanghai Somerset West St. Louis Sydney
What is pharmaceutical compounding?
Patient
Tailor-made medication
Compounded in community and hospital pharmacies or by Fagron Compounding Services, always based on a pharmaceutical formulation Formulations developed by Fagron
and/or compounding pharmacists
based on APIs which are out of patent Alternative dosage forms
Alternative dosage strengths
Combination therapy
Key drivers of pharmaceutical
compounding
Unique selling points
Prescriber/Pharmacist
“Yes, compounding pharmacists enhance medication compliance and save lives… every single day!”
Drug shortages Discontinued drugs
High-quality and cost effective alternative Less side effects
More individualised approach Tailor-made
Enhance patient compliance New and unavailable therapeutic needs Increased awareness through internet
Business model
FCS
Fagron Trademarks
Fagron Compounding Essentials
Raw materials Excipients Equipment Supplies
Nuclear, Sterile, Aseptic and Non-Sterile compounding
Fagron Advanced Derma SyrSpend® SF
Fagron compouding advisors
(EU: 300, NA: 100, SA: 100)
Discuss patient case with prescribers Tailor-made medication prepared in a compounding pharmacy or by Fagron Compounding Services Formulary based on Fagron APIs and Fagron
Trademarks
Encapsulating the compounding
market
Win-win-win strategy
Prescriber Pharmacist Patient Patient organisations Government Insurance companiesOur unique position in global
compounding
Global market leadership
Optimising and innovating compounding Extensive R&D pipeline
Unique business model Strong brand names Global footprint
Our unique position in global
compounding
Group strengths
In-depth compounding knowledge Use best practices
Speed of execution
Extensive global network Local market expertise
Acquiring and integrating expertise Solid financial position
Our unique position in global
compounding
Operational strengths
Global scale benefits
Compliant with highest quality standards Product portfolio optimisation
Centralised purchasing Production efficiency
Proven buy-and-build strategy,
generating sustainable value
Tamda (Czech Republic) Unikem (Denmark)
Gallipot (USA) DEG (Brazil)
Florien (Brazil)
Three compounding pharmacies (Colombia) Orbus Pharma (Colombia)
Galfarm (Poland)
Apodan Nordic Pharma Packaging (Denmark) B&B Pharmaceuticals (USA)
Freedom Pharmaceuticals (USA) Alternate Technologies (Brazil)
2012 2013
2008 2009 2010 2011 2014 2015
JCB Laboratories (USA) Pharmacy Services (USA) Kertus (Greece)
Fagron Australia
Dynaceuticals and Rausa-Kem (SA) Pharma Nostra (Brazil)
Pharma-Cosmetic (Poland) Pharma Assist (NL)
AnazaoHealth (USA)
Accelerate buy-and-build strategy
with focus on FCS and Trademarks
FCS
Fagron Trademarks
Fagron Compounding Essentials
In % of total turnover
Q1 2015 Target 2016
37% 50%
10% 25%
Business model: FCS
Tablets, capsules, liquids, crèmes/ointments
IV-Bags, ampoules, vials
TPN, cytostatics, syringes, cassettes, easypumps Radioactive capsules, radioactive injections, radioactive seeds Aseptic Sterile Non-sterile Nuclear
Fagron Compounding Services
facilities worldwide
Belgium
Bornem (non-sterile and aseptic)
France
Paris (non-sterile)
Marseille (non-sterile)
South Africa
Johannesburg (non-sterile)
Cape Town (non-sterile and sterile)
George (non-sterile and sterile)
Greece Trikala (non-sterile) Colombia Bogotá (non-sterile) Bogotá (non-sterile) Cali (non-sterile) Medellin (non-sterile) Netherlands
Oud Beijerland (non-sterile and aseptic)
Helmond (non-sterile and sterile)
Hoogeveen (non-sterile and aseptic)
Oldenzaal (non-sterile and aseptic)
Goes (non-sterile, sterile and aseptic)
North America
Wichita, Kansas (sterile and aseptic)
St. Louis, Missouri (non-sterile)
Arlington Heights, Illinois (non-sterile)
Tamarac, Florida (non-sterile)
Tampa, Florida (non-sterile)
Fagron Compounding Services
Warehouse incoming goods Clean utilities Transfer into clean room
Fagron Compounding Services
Prepare for compounding Compounding Visual analyses
Fagron Compounding Services
Growth driven by increasing demand for sterile compounding
Compliant with the highest, most stringent quality standards
New antibiotic facility in NL will open in June 2015
New sterile facility in USA will open in November 2015
More hospitals are ready to outsource compounding
Actively looking into potential acquisition targets
Estimated market share <5% in the US and Europe
In 2014, Fagron prepared over
2 million prescriptions
Fagron Compounding Services
Acquisition of AnazaoHealth
Leading nuclear, pain and
intrathecal compounding facility in the United States
2015E Sales of US$ 30 million with an EBITDA margin equal to Fagron
Acquisition multiple 6x EBITDA Headquartered in Florida and a FDA 503B facility in Nevada
Nuclear compounding
Nuclear compounding is a specialty area of pharmacy practice dedicated to radioactive materials for use in nuclear medicine procedures, which includes cancer treatments and diagnostics
Radiopharmaceuticals are radioactive. Radiation protection during compounding and administration forms an integral part of the job
Anazao’s radiopharmaceuticals are tailor-made compounded as capsules, seeds or injections
Radiopharmaceuticals administered as injections are compounded under aseptic conditions
Investment rationale
Specialty pharmacy compounding presents huge growth
opportunities
Growth drivers for Fagron:
•
Ongoing trend to outsource compounding
•
Increasing demand for compounded medication
•
Decreasing number of competitors due to new regulatory
requirements
Acquisition candidates in South America, North America and
Europe
Fagron Trademarks
Growth driven by the global launch of Fagron Advanced Derma and
SyrSpend® SF
Global Fagron R&D network of >300 pharmacists and 45 researchers
Global presence boosts cross selling and innovation
Increasing interest for Fagron
Trademarks by pharmaceutical industry Strong and extensive R&D pipeline R&D pipeline includes concepts on psoriasis, alopecia, transdermal pain
Prescribers worldwide: compounding
prescriptions based on Fagron vehicles
Global R&D
Total spending R&D: 8-10% of turnover
Development Realisation Launch of solution Patient, pharmacist & prescriber
Global R&D pipeline
Launch Global Concepts
FAD phase 2 Pain, phase 1 SDD FAD phase 3 Obesity Alopecia
May Jun Jul
Jan Feb Mar Apr Aug
2015
Sep Oct Nov Dec Feb 2016
Aug
Fagron Compounding Essentials
Central purchasing and audit office in Shanghai, China
Complete offering of 5,000 raw materials of pharmaceutical quality Full overview of supply chain
resulting in 100% traceability
Unique selling points are product availability and quality
Potential add-on acquisitions in existing markets identified
+39% +165%
Financial highlights 2014
Turnover (in € million) 447 OWC (in % of turnover) 9.1 Capex (in % of turnover) 2.8% Gross margin (in € million) 288 REBITDA (in € million) 118Free cash flow
(in € million) 57 Dividend p/s (in €) 1.00 EBIT (in € million) 94 +30.4% +48.1% +49.8% +42.2%
Organic turnover growth of 11.5%
Gross margin increases to 64.5% of turnover
REBITDA growth driven by focus on FCS and Fagron Trademarks and continuous focus on OPEX Net financial debt/REBITDA ratio of 3.18, compliant with covenant under the credit facility
Free cash flow increases 165% due to increasing EBITDA, good working capital management and decreasing taxes paid
Outlook 2015: Turnover of at least € 500 million with a REBITDA margin of 26%
Organic and total turnover growth
Fagron
9,4% 5,9% 7,2% 6,5% 10,9% 13,7% 11,5% 24,2% 10,5% 18,3% 35,8% 21,8% 20,3% 33,0% 0% 5% 10% 15% 20% 25% 30% 35% 40% 2008 2009 2010 2011 2012 2013 2014Total growth at constant rates Organic growth at constant rates
Q1 2015: Turnover per segment
In € 1,000 % of total Q1 2015 Q1 2014 Total growth Total growth CER Organic growth Organic growth CER FCS 37% 42,815 19,778 116.5% 101.8% 41.7% 32.1% Trademarks 10% 11,594 10,658 8.8% 4.6% 8.8% 4.6% Compounding Essentials 53% 60,543 57,838 4.7% -0.4% 5.3% 0.2% Total Turnover 100% 114,952 88,274 30.2% 23.1% 16.8% 10.5%Excellent start of the year
Total growth of 30.2% and organic growth of 16.8%
Very strong growth at FCS, the segment with the highest margin
Continued focus in 2015 on robust organic growth, an active buy-and-build strategy and the construction of GMP-compliant compounding facilities
2014: Turnover per segment
In € 1,000 % of total 2014 2013 Total growth Total growth CER Organic growth Organic growth CER FCS 34% 147,780 58,210 153.9% 153.2% 20.1% 19.8% Trademarks 10% 45,652 33,630 35.7% 39.8% 24.6% 28.4% Compounding Essentials 56% 245,047 243,145 0.8% 3.3% 2.1% 4.7% Total Turnover 100% 438,479 334,985 30.9% 33.0% 9.7% 11.5%Without the disposal of € 10.9 million of Industry
Sales, organic growth of Fagron Compounding
Outlook 2015
Fagron expects to realise a turnover from
continuing operations of at least € 500 million
1with a REBITDA-margin
2from continuing
operations of 26%
Shareholder structure
Number of shares % of effective voting rights
Carmignac Gestion 2,463,267 7.84%
TIAA-CREF Asset Management LLC 1,635,681 5.20% BNP Paribas Investment Partners SA 1,609,182 5.12% Fidelity Management and Research 1,573,158 5.00%