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TiO2 Nanoparticles Induce Lung Fibrosis and Proteinosis through Influence on Matrix Metalloproteinase Expression

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Figure

Table (2) Ended weight and organs weight percentage of rats during the study.
Fig. 1. Histological section of lung from (A) the control group and (B, C, D, F, G) treated group with (0.5, 1.5, 0.5, 5, 15, 50, 150) mg/kg of TiO2 NP respectively, after 4 days from intratracheal instillation, (A) showing the normal structure of alveoli (thin arrow), terminal bronchiole (thick arrow) and normal alveolar lining epithelial (heads
Fig. 2. Section of lung from the control group (A, B) and treated group (C, D, F, G, H) with (0.5, 1.5, 0.5, 5, 15, 50, 150) mg/kg of TiO2 NP respectively, after 4 days post-instillation, (A, B) showing the normal bronchus lining epithelial (thin arrow),
Fig. 3. Illustrated the alteration on lung of the treated groups (B, C, D, E, F, G) with (0.5, 1.5, 0.5, 5, 15, 50, 150) mg/kg of TiO2 NP respectively comparing with control group (A) after a month post-instillation, showing lymphocyte cluster in alveolar
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