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The different forms of collagen and gelatin

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(1)

it

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of

(2)

PHYSI\' SCIENCES

_!JflRARY THESIS

(3)

F<Y

1.

t n, oo • i a t i ot

true

n or o

t r of t ns. It ie 111'

oro to

be 00

e acid or

ell t1 of l • t. l

a n

nrr to o

t

u

:r in

ion. t

0

i :ren it n of -C-N-C 0 n.

0 0 or i of

conv·e to

1 of :r t

(4)

t t

ns so

t t s 11

d f ( l)

t io c of iso- c

RlOl llows:

le ion of

is coll

i ti ve

j t ern a is f

(2) iUlti, f~!!l th mec ems

an ins t) ructu:re ()f' the , an l

v i l l be f~

i t t col 1 i

ot 1

0

b 1

t i in 0 (.., )

t tua d l 1

() i 0 1

(5)

roes b t ( (

a $

on

1r ou

ret ti sue.

n of in

t of' co .. o 1

+

to te in

(6)

e

I I ..

ool

ar

• in eo

ill revi

1 t n is to b

V~J

enc e of of

Uf> as

t

sol

l

t

( 4)

aocor ng

0 R U R

II

\ /

{

/

c, /a"

"N/

c/ \;

r~,

/

I

II

I \

H 0 R Jt

o form effect o.nlv.

0

i

t ao

in

t b

i t

t

i

(7)

11 nee of

acid. t r e a t m e V

~lkali

treatment

(8)

d not been di

in of t

0 t

to b

t

6.

t

ect is cono

1

(9)

T

1

8.

(10)
(11)
(12)

t

i

t

t 1 t

t

(13)

n

on o r~

or

t

not :r~11cr bl it i fJ

t

oru

o.f

l i

r

in 1130

to

,.7

of t

1 t :r !!H!V ~l' 1

t it

in ocnnot b reaa

to

:r t

th

l!l ( 1 1'. 24.)

n

r

11

i l

l i

t

(14)

1 renct n over t f i t

in t 'P in

t to

."'

a

1 1 1;0

ur

0 "

coo r t a t "

on

n t m!uie

over

uo:r to \P• I

27

)

Gg~c

-

-(: .;H;;ific rot n 0 io 0 ti in

" ic n

l'Oflt

-

f

oi' In

0 1 in ecific

rot

n n~?a,r t n

1 e.

r 1 0

r

i

'

over

p p on t on

c ion, 1. ( 31.1

curve t acid on

ll!I'!')ISC 0 in e b to curve

~ \RO

i t

(15)

1 •

rot r1, it lJ t

t

ion t uol Nl 0 g

le

di (

'

n

ion

of t b tu:re

an

rh:&e

() f

i;

of' t

a (>~.

"'•

:FJO

in f

s ia c

ti:n· a

of ( ~!H~

* I Pl.).

27

31)"

~ h curv

d t'ect of oid on if

in rl

'P of t

r

tin Y1!'0

re

eu

1 !' reac on~J ..

(j' ,I so

II

or

t II

for

i 80

l'' '·' i

11 r:m 0 &

ana

(1

of t i

1 0

(16)

;;~eco val b t

t

·'11!11."\1' a i Ue ( \. i

ion t on 1J rot, rrwl

i'\1 n :r a en ~a:

( )

,..,.

+

...

+

( ( )

a.G or· 1

co

n not

t

,

ac:i so

t to c

i

''

"'

c

t l;;J.. 1o

'\H'"l~no foro to 0 t !1U in

(> d. i \~1"

n.

a 1 t f () f 1i t

b ju )

1 0 l.

[~. ao t i

1 n d

1l 11

J

...

co9

c-eo.

I

-

c ..

I

I

I

I

ll H

~]=

(17)

"

urs

l

...

(18)
(19)

( )

0 t

of

1

i

I I ..

t

3

to

t

1

i.on

nro nounc

ion o

8

in

not

of 1

i

:muoh

t

i

1 h d.u

id 0

aol i

(20)
(21)

2..

)

6.

(

)

(b) (c)

co

to

l

un

no

i

n o

of

n i

t b

1 t

d

ion I)

i

irA

io t

£101

con

in t

i l

ri

t l 0 t

act~

c

1 1) ord b i

t

(22)

..

in t

• • s of ol

itro

'00

er

u s

no t

no j

U1i1 of \l

1i

t

bic

of t

0

f

(23)

it WO.I:l

i i

error i

b

cc

in

in

to

ion

ion i

iiJ rot

l

0 co

t

ot

t en

r t

ro

QO • i

+

- l.

t di

of

CQ

room

of t

t

(24)

ll.

In

r t t 0

o ..

~0

or

pr

' Wf'l,~

swo en in 0 ,,a i l l fL

t, Oil er- a.

so cool

(

c

) for ur m. t t s

to a t at; ~ or

urs.

tr

fl er me~.sur s on one 0

eo ions$ sol n(~ l'Ui i

(25)

ur so t

A• B, C,

1) ~ ~)I'

sao in

a ceo

nr

n A o,ud E wer~ !;!Ci r

of t ~tJolut e

.

..

t so u ann to

7

un e:tc 13 of no so

0

u

an j)

i l l

er.

It not nee

r

t so ion~~.

1 r ion of .four ~10 l u. n

y;,: rvwl of t

..

result en 1

(26)

U) (J) Q) ~ Q() (J) q ~ •rl ~ o · ·rl ~ ("j ~ 0 (Y; 0 •rl '+-! ·rl 0 (J) p _ (f) 0

Specif ic Rotati on at 20 C of Solutions of Ge l a tin in H/10 lJaOH and of JJe u:tr ali sed

!"'.,. ... -,--- ~

T

T -

I Co ntrol Solutions

~ _...,. .. ~t· • - - - ... --- ..

- · - · - · - · · .;llj . . . .

CONTROL SOt.IJTION fl PI..O TTED 11 5

---1---- .. ---

.

~

...

.,. ..

-

~

....

I

CONTROL

Hjto tv .. Of/

"fo/IIAQH

Qj,O ·-~·~•--·••t

..

J• ... 4.- . . . ~

l

1

. , • , ' I

SOtU/f OIV 8

SOJ..r.JT/0(\/ c

SoLUTioN 0

+'-• - ..

4-I

I :

I .

.

.

I

' --

~- -~-

... -..

~

...

).._---I ' .

l

! .

' • I . I I

·---c

j,OO .. • ... ""' - T' ... r • """ ... + - - t · ... -; ---T - • t ~ r

, r i '

' ' I ,

.. ~

..

..

-·--

~ e e 0 0

I '

I

.._ .. + .... • 1 . .

:.1_

t •

I ! • I I I ' ' I

..-..+-+ • ~ - 1~---f - I • ._ t t---~r

. t

----+

'"'"' .,._

.

~--...,_.,.,_

I . '

• t f t 180

.

'

;/o

...

_

...

--

-·---I -·---I

~

.

-r- .... ... ~ ' .. + ... ·~ .._ ... - ... .

'

.

/1,0

t ' , I '

-+: ...

;__;_r..I~~J::

f

! .

I I

.ro

7-0

-·-1 ... -,., ....

?o

~ --- --+ •

I

~ l

-1

1 '

j/0

I

! •

'

:

[

.

'

I

I

t

·-I ' • ' 1

I I

...

-·--·

--·

--· . - . ·r .. .,. ...

, ,

r

T , . ~

• •

1 '

' t

. I : ..

*

!

--:r·

. i

130 !SO

-.ge of sol '1t i ::;n i n ~!oars.

9 e

e e

0 0 0 0

I

·~

.

t-~

.

9 · ~·--~if...-..-· · - I I •

e ' ' ' '

'

-0 ' I I

0

·-.

I

-

-

'

....

...

""

I

-:

' . l

-u~

• ~-' ----1

' . I '

I •

I • • l 1- •

A. - + - ~ ~ ~ .

.1111. . . . _ . . ...-.+-+,..A

• t

.. ~ "" t ' ,. '

I

•···-t·•••t

~ ~ .. • . t • • • • ' '

-~tl · - - ~

1 , + 1 .

I

r 1 1 - t;

~ • ... t· • -_ l

!'lO 190

(27)

n r

.

)

1 .

(1.

.per

.

}

@

3-

.9

(28)

71

95'

197

(29)

t u.r ao ll j ' ' G

'

to t t')rev

ecrib G H

were

1 cc.

or

VO euc aolut ion

to

oc.

f lly a t normHl fl!O

ion

of'

co t t of i f

U5i9d co rola.

e l ion 0 f' our eo

t eM'~,, l t

nr: OIJ t

r t ur 1:10 ions

11 1n 1 9

v.

1

are t so

t 1 ta t

(30)

r....,..-~

Th e effect of t h e a dd ition of N/10 NaOH on t he specific rotation of g e la t i n at 2 0

°

C •

-1

l

I :.t.tJ +

J.P t I

t I

. '

~-e

---t

I '

I •

e

e

. -. -·-1 .

. . I .

• t-1

+-- ...

-+·-e t ' I I t

e

... +

..

I

I

. . . t .. • 1 ' ~

Ul d CD 0 ... I-I;) 1-'· 0

---~----+--

... - -

·--·--+---J.----~·---·

I

. . l

..

~--·

~ \0

0

c+

·ttr..:..!_j·t··

-+-4-~--·_,....,r-'1'"""._ .. , ~~~

...

-r.t-!l' c+ 1-'• 0 ;:s 1-' ·

:::s ;eg

o.. o

---r---.

! · -t::t CD Gtl 11 CD CD

U2 0

!bO

!

~ *

t •

I

I

l "

r . e

'f • I t ' t ,.

e

' '

,._. * .

-

'.

'

.

I

' '

CONT/l 01.. SOL iJT ION

CONTP, Ol. SOI.VTIOIV Njto IVa OH St>l. O TION

-

.

N/'t>

IV~tOH SOl.fJTION

t--'

I

I

;.,

; . r

:~

-r-

~ ...

-

...

-_ .

,

. . . '

0

0

j I · " t

.!....4---4-l-+++-+--r-~· -1---~-+--- . ....,. .

--·

' ·-- ... ---~ .. - . -

4-, t

fii(J

.

-

.

t·t t· t- ,_

'"

1

I ;

!' ..

-1 .

t • ~ '

l?o

t- " - ... _,_ - - ..,..___ .... T

-/t7ZJ 1-10

Ag e of solution in hours.

e

E" Pl.tJTTEO

F ,,

ct ..

H

--..

-l

RS e e e

~

.. 1-'·

.. 0 0 0 ~

... + ,...

· · •t ·

' ! " '

t

-H H C/) (l) CD 1-3 Sll o" ... CD U2 H ~ sn ::l P.· <: ·-l

(31)

(

..

6

00")

a

l. .. 6

l ..

.o

43

1.

.13

1~

.a

1.

.6

136

1. .4

(0.

.

oc .. )

1 •

·3

44 l.

..

.6

2.

.6

l ..

·9

(32)

(0 .. per

oc.) l 1 ..

73

1.

..o

1.

-.7

l. "(j

47

1.

·9

l.

.8

76

1. 4.~

1-

·3

1 •

-9

..

... ...

-

..,

-

...

..

• 1 ..

76

·9

l. .4

1 ..

-7

16

1.~7

.2

1.

167.4

l.

167.4

73

1. ~4

1 ..

·1

1..

<>1

(33)
(34)

.

)

2 .. 19

9

l 2 ..

11

0

2 2 ..

.6

3

2 .. ..4

4 2. ..1

'

2.

.. o

1 ..

.9

1 ..

3·6

1. "

1 ..

.6

1.93

.. 4

1 .. .. .2

1 ..

"

l. 9

1 ..

.s

1.

1

l ..

.6

1.

6

l.

..6

·3

l.

.)

l.

(35)
(36)
(37)

(0,. p

00.) 4

2 ..

.6

7

2

·3

2.

..o

1.

2 .. 2 .4

1 .. ~5'

l .

.6

l .. 2

1- .4

1.71 .4

116

1.

.o

l.

·1

(38)

(6.

cc,.)

t

2 .. .. 1

1 2 ..

..6

2 ''J

""

..;

4 2 ..

..

;

5

2.17

.. 4

6

2. .. 2

7

if'"',

~. .1

2 .. ..4

2 .. 4

:2.

.6

..

·5'

1 .. .4

1. ..4

1 .. ~3

l.

.6

73i

1. 1

1.

..3

1 ..

..6

1.

.8

1 ..

..6

1 .. ..2

(39)

(a)

(b)

(c)

c

( l) 000

( )

(3)

• 34.

.. "" 46.

-

-

• 63.

(40)

34.

1:r 0

t ua

t ions are d ficul t to

t

00 int of tt s

or

t

eot c poi 1

due t 0

i t d

t curve

t Ci erent

on t .. in

ion 4.

8

1:iOI1 one

(41)
(42)

90

t,

ua

..

t 1 •

BOUI'CHH'!

t

co it

t 0\l:r'VB on

re

ot 0

e1 00 a

..

ch\ t

um

r e, ere () no t

viaoo v.:,,

in

u

vioco

t n u

r

t

lu

L

t th

e waa chosen in nr erenoe to

1

ion 1tae

eot

io of tr

d 0 eo n

of'

0

n

inoe i

ev

of t

t

Yi l inu iu

ne

r

~HJt on ea.

n r~:rp

entt

n of

to

1

to

(43)

80

()) to

i>

·rl

+' ;.\)

.-I .; ()

(])

~

)()

b()

Fig. V. L/{tiED (OLFSKIN /IT k1J0

e_@

lSEE Fl(.

YJL!)

/JCIO Plt:SI< /IV /IT IJIJ "e

(SEE Fl¢ (KJi)

90

q II 3

.s

7

CGt.RTI/11 Ff{(JM Hlb£ .SWOLt..E!V

1/V

JVfttJ

NA f)H {SEE Flt:.X/1)

CEJ.IJTJN FRNVI HI()£ SWOLi.EIV

IN '¢o Hcf (s£E Fit:. X))

3 S ] 9 II 3 .r 7 9

pH

~V

1scos1 · 't y o f' 1',zo· p ge a 1n so u 1ons 1 t · /JH1-7t ·

,,

II

io

/(jt7!J :>:,

+>

•rl U1 0 jS()zJ ~

[image:43.605.45.523.108.769.2]
(44)

lt

wa

!'5 le to u e n

,

e~ co .t'Ol

a a (l

on t vi~;~<llo "' .._, aoco 00

tro 1 t' n 0

er

not '<'S:'f

"'

t::lrld 1!:! ion of B li*IOO

,:;ve co

{ ) roe of 0 1

eino 1

wo

t sia 'NO our 11

COtlO

n.

a t e io on t'IO ftlrm () +c+ k in

• p t r~~ot dtlC eo1ution i

'PO 00 eon so of

b 1

r t

"'

0 1 of in ion 1a er1

1•"lrenoe in t it

more

i N::st

:~:• s t t, 1 so

..

soo () f'

n io v u

0 to f i t. te di u~ n t r

0 (;) I:JUI'VE!!'J frorn t E'!O

v.

Ut'~'

\"'',' curve t 0 r

"

visoo 1

ou

for

tin ( no • t i t

(45)

VlJ

3,

s

l:Y

&

to va

ourv b 6

H1

0

~~,m

curve

in (

"

ft~)

1 r in

in.

i c 'Point

t 1 0 n

eco t

of

GOO i

2 ..

t t t t <Stn!.i

3,

e curv .;

...

1 een

5

1

co

"

!nl..lm

on

9,

4 .. 1l ..

to

of 1

• SOOt-1

7

1 tlO een :It

carve

t 1 n 3 id

4.7.

" ~ " i!JO•

1:n 11

1

r 1

9

8;

n ti

in

not f!C

(46)

of

t

1.

(

ui

er

on

~it

not

8

0

sence of

ll

i)H

curve

i not

curve for t

t

., ~n t ou:rv

(!~'

~)

1lii

pi

f

Vi

eo t

r

0

in t

curve

t

tl t

i

-id

f CUI"Vl!

curve 1

..

(47)

Fi ~·

VI.

en

@

®

rd

LIMED eru.FS/ll/11 /J~ID PI( SKIN

s:::

0

/1.,() OISJOLVGIJ flT 7S"e /)ISS()(. VGJ) /JT 7S0e_ Jl.t(} 0

Q)

{SEE Fttf.c:tll) (SEE Fttt.EJj)

UJ

s::: /P,(J ~~~

•rl ~,. ,...:. ·rl /C!lJ Ul 0 0 ro

·rl 8o

p

<:)

p

~

t'o

m

n

Q)

r~ 3 u II 3

s

') 9 II

j:JH~

/>H----:7-ill---=~--.---~---~

(j)

(f)

•rl

g

1·80

·rl

+l

s:::

Q) /

0 /'(,()

s:::

~.NP

,...:.

·rl UJ

g

/·~/)

lfJ

•rl

:>

QJ ;,tto

+"

::s oi

©@

L/MEO CRJ.FSKIN

IJJ$$0LVEO fiT 4P°C.

{HITCH t'Otl<)

t·to

tf$'4 NTIN OISSOI.VFO

~~ 7.S "c

{0!1V1 S f1fll0 t>liKES)

NJO

0

rn----~~--~s ____ _ L _ _ _ _ ~9~--~~~~---J---=-3--~~~--~?~--~----~'I~---J

~ pH-? PH-7

(48)

t

til 0

BO i

of' o visco

.

( c ock ( )

t

t;

(49)

0

r r • b

ns

fro visco i

au.r

r i e es

are on th sa:m~tt

"

1 Q f .. !I

l

'"3f

a

t

t i

ion

In

t t t

1 Q J' l

t

n

e

e.

of t, t CHH!

t h t 0

I'~

t 0 b

(50)

in f 0

an

{

)

1

.B. hn

0 t t

of'

on c~~

6 •' ~

7,

8~ and. '].

ieo-l i b 4 snd

co l 0

00 of c

7.

B

co no l ne of

no i

e CJ r::' •" d. t • li t

6_

line err 0

t ·'

tl

on t UF

'

r;;

¥1' ~

0 l

4

i

Iii 1

(51)

GO

i

in

of e 1 t co

means of t

00 d

(52)

l.

aoos curve~ r

{a}

n

(b) n g in

(c) Aoid. in

(d) s.c

(e) Ge

e

t r:J f f:)tl i f' t

fl n not

..

n e 1 0 ...

ec

(

)

p 0

)) in t 4

...

t: / ~ 1• ,,

..

,. 1

ni tin in the

7

...

8.

Vi i GUr

• • 1

4.

'

ann ll

'

i

i

no

tion tin '!)OS i l

i not

ur t i

(53)

or

t d

..

7- rcit"~ on t viaoo

t t,

~-n e

(54)

"

i ~t)•

fro 0!'; ru

"'

o.

1&

...

"

pH of so lutiorl

..

4.6

orii pi r.l. in f':renn 1 n

( Co.)

2.

1

on

-

5~8

t t i b

n

...

o •

i

...

of solut "'

4.9

pi

f~ tirl <ie aoid ni

ns.

(

.

)

"" 2 ..

i

...

(55)

v

{ )

.

t

t(J one

en me fUl exo t

t n

"

...

o •

i

...

of eolut ion

...

in so

(see p. 109 )

(ee

rnen

er

.110

t

)

• "

cl then

i

11

in c rn. in

..

the n been

,

..

,

1-t 00

o ..

.6

.o

co t i

l dri i

(56)

of in, wns we 0 in co.

co. 00.

t

1 0

t

n

:fro

iso ..

lo

in t :f t room t

ur

..

plac t

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