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Antibody mediated targeting of the FGFR1c isoform increases glucose uptake in white and brown adipose tissue in male mice

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Academic year: 2020

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Figure

Figure 1. Effect of systemic treatment with a monoclonal antibody
Figure 2. Representative whole-body PET/CT images of euglycemic mice receivingtreated with (A) vehicle (saline), (B) H7 + vehicle (saline), (C) vehicle (saline) + insulin, and (D) H7 + 18F-FDGinsulin
Figure 3. In vitrovehicle, IgG1, and H7. Values are group meantreatment). (C) Basal cellular respiration, ATP generation, maximaloxidative capacity, and nonmitochondrial respiration in adipocytestreated with vehicle, IgG1, and H7

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