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Incubation of ovine scrapie with environmental matrix results in biological and biochemical changes of PrPSc over time

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Figure

Figure 1 Incubation periods of mice after challenge withscrapie. Mice were inoculated with extracts of soil incubated with apool of classical scrapie isolates or with a dilution series of the samescrapie pool without soil incubation g/mL of brain inoculum
Figure 2 Representative images of PrPwhich are associated with AplSc deposition in the midbrain of tg338 mice after challenge with scrapie
Figure 3 PrPSc characteristics of the scrapie isolates. Nine ovine hindbrain samples that were pooled and incubated with soil (a) wereanalysed by western blot

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