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A Novel CIAS1 Mutation and Plasma/Cerebrospinal Fluid Cytokine Profile in a German Patient With Neonatal-Onset Multisystem Inflammatory Disease Responsive to Methotrexate Therapy

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Figure

Fig 1. The patient’s CSF cellularity aswell as IL-6 and sTNFRSF1B levels inthe CSF over a period of 10 months.sTNFRSF1B concentrations were onlydetermineduntiltheageof36months, whereas the measurement ofIL-6wasstoppedsimultaneouslywith cessation of intrathecal MTX ap-plication after the development of achronic subdural hematoma at theage of 46 months.

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